Research Insights
The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.
Ultrasound-triggered doxorubicin targeted delivery for liver cancer treatment: Reduced toxicity and improved efficacy
Liver cancer especially hepatocellular carcinoma HCC remains a major global health challenge causing high mortality worldwide Conventional chemotherapy often results in severe side effects due to its systemic distribution
Risk assessment for cardiovascular adverse drug events in the ICU: Case study on COVID-19 patients
The COVID outbreak quickly became a pandemic In Brazil more than seven million cases were recorded in
Topological stratification of continuous genetic variation in large biobanks
Biobanks now contain genetic data from millions of individuals Dimensionality reduction visualization and clustering are standard when exploring data at these scales while efficient and tractable methods exist
Non-immersive virtual reality telerehabilitation for motor accuracy and precision in individuals with Cerebral Palsy: A non-randomized clinical trial
This study aimed to describe motor performance accuracy and precision in individuals with Cerebral Palsy CP compared to typically developing individuals controls and to examine longitudinal changes during a nonimmersive
The Nottingham recovery from COVID-19 research platform (NoRCoRP): Functional, clinical and patient-reported outcomes in adults referred to a post-COVID respiratory service
To characterise symptoms function and patientreported outcome measures PROMs and identify associated factors in adults with persisting respiratory symptoms postCOVID
Predictive divergence in machine learning models for clinical mortality risk: A multicohort study of covid-19 patients
Machine learning ML algorithms are increasingly used in healthcare to support clinical decisionmaking While models with similar
Assessing the biopotency of the rAAV9 vector In Vitro
The potency assay is critical to ensure the effectiveness and consistency of recombinant Adenoassociated Virus AAV gene therapy vectors especially clinicalgrade products AAV serotype AAV
The synergistic interaction between ACE and TMPRSS2 polymorphisms increases the risk of severe COVID-19
Within a few years after the pandemic outbreak several of evidence have found to suggest that the genetic factors influence the severity and mortality rate of COVID
Protein-interaction network analysis reveals the role of Prp19 splicing factor in transcription of both intron-containing and intron-lacking genes
The process of transcription and cotranscriptional mRNA processing are facilitated by myriads of molecular interactions To elucidate the proteinprotein interactions
Safety population size and duration of exposure prior to approval of new medicines: A database analysis of medicines centralised approved in the European Union between 2011 and 2023
This study aims to analyse the number of patients who had been exposed to a new medicine before the approval by the European Commission EC as well as the number of patients studied longterm for chronic medication use
