Pharma Focus Europe
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Research & Development

In every industry, research and development are crucial. Biopharmaceutical research companies use R&D to bring about many results, including saving lives and enhancing the quality of life for patients. Companies in this industry rely on reliable pharmaceutical research and development services to keep them up-to-date with manufacturing procedures and quality control measures.

Using AI to Accelerate Drug Discovery

Quantitative systems pharmacology (QSP) combines computational modeling and experimental data to examine the relationships between a drug...

unlock lab efficiencies and decision-making through a digital-first approach to lab transformation

Recent industry pressures brought on by the global COVID-19 pandemic provided critical lessons for the life sciences industry...

The Future of Integration of Targeted Therapy with Genomics in Personalized Medicine

One in five people will be diagnosed with cancer in their lifetime, according to the International Agency for Research on Cancer.

Rare Diseases Medicine: Advantages, Challenges, and Future Developments

The challenges associated with rare diseases are numerous and multifaceted.

New Pharmacological Targets and Biomarkers for the Treatment of Tuberculosis (TB)

Mycobacterium tuberculosis (MTB), which has harmed people for more than 10 decades, is the cause of the chronic lung infectious disease known as pulmonary tuberculosis (TB).

c-MET Receptor Tyrosine Kinase: A Potential Biomarker for Cancer Therapeutics

C-MET is a tyrosine kinase receptor in the MET family. Normally, it is expressed on the surfaces of several epithelial cells. HGF/SF is a common ligand of c-MET receptors. Cooper et al. were the first to identify the MET oncogene in 1984.

Effective Biomarkers in Uncovering Novel Target Molecules for a Drug

The Revolution in New Drug Targets

Biological markers or the more commonly used term ‘Biomarkers’ was first heard of in the 1950s. In the coming years, this term gained unprecedented popularity as myriad studies were carried out regarding the efficacy of biomarkers in the drug discovery and development process as well as in the medical diagnosis of diseases.

HYBRID EXOSOMES: A Novel Platform for Cancer Therapy

Effective cell-to-cell communication is essential for normal physiological homeostasis in multicellular organisms like humans.

INTEGRATIVE ASSOCIATIVE CLASSIFICATION FOR CANCER BIOMARKER DISCOVERY

Biomarkers or biological markers cover a wide range of substances that can be measured from body tissues, cells, blood or fluid. For instance, a cell expresses genes when they are required for biological processes, and the measurement of gene expressions under different physiological conditions provide essential clues of gene functions. Therefore...

DIGITAL SOLUTIONS IN DRUG DEVELOPMENT

Regulations to enable safe, effective, and high-quality solutions

From mobile medical apps and fitness trackers, to software that supports the clinical decisions that doctors make every day, digital technology has been driving a revolution in healthcare. As we learn to live in the new normal, forced by the COVID-19 pandemic, adoption of digital solutions has witnessed further acceleration.

THE FUTURE OF RESEARCH

Importance of accelerated clinical trials for evidence-based treatments

Over the past year, the COVID-19 pandemic has heightened the urgency for clinical research to understand the disease, uncover treatment plans, and develop vaccines to treat a disease that was once unknown to the world. It was equally crucial that findings were swiftly made available to the public, to prevent misleading information from undermining...

Immune System and COVID-19

Management and potential therapies

In December 2019, a pneumonia outbreak occurred in Wuhan city of China that quickly spread across the world and posed serious public health emergency. On 9 January, 2020 novel coronavirus severe respiratory disease syndrome coronavirus-2 (SARS-CoV-2) was identified as the cause of outbreak in Wuhan.

The Promising Future of Stem Cell-Based Therapy for Kidney Diseases

Kidney disease is a prevalent global health problem. According to the World Health Organization, as many as five to ten million people die annually from kidney diseases worldwide. Chronic kidney disease (CKD) is projected to be the fifth leading cause of death worldwide by 2040.

LIPOSOMES IN THE CREATION OF A COVID-19 VACCINE

Messenger RNA (mRNA) is a versatile and safe platform for the expression of proteins. Unlike DNA, mRNA is not integrated into the host genome and its translation machinery resides in the cytosol.

ENVIRONMENTAL AND SUSTAINABILITY REQUIREMENTS IN DRUG PROCUREMENT

To preserve a healthy environment and human well-being, there is a recognised need to move away from overconsumption, waste and ecological harm.

The Role of Biopharmaceutics in Early Drug Development

Biopharmaceutics is a major branch in pharmaceutical lores which relates between the physicochemical parcels of a medicine in lozenge form and the pharmacology, toxicology, or clinical response observed after its administration. medicineefficacity and safety are dependent on the dosing authority. The optimal lozenge and dosing intervals can be rela...

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