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Research Insights

The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.

Acteoside and Isoacteoside Alleviate Renal Dysfunction and Inflammation in Lipopolysaccharide-induced Acute Kidney Injuries Through Inhibition of Nf-κb Signaling Pathway

Acute kidney injury is a severe clinical and multifactorial illness characterized by a sudden loss of renal functioning It is marked by impaired renal tubular reabsorption and decreased

Evaluation of Genotoxic Effect via Expression of DNA Damage Responsive Gene Induced by Ivermectin on MDBK Cell Line

Ivermectin is a semisynthetic macrocyclic compound which is effective against numerous parasitic diseases including onchocerciasis It has been reported to be effective against symptomatic alleviation caused by Onchocerca

Genetic variant rs1205 is associated with COVID-19 outcomes: The Strong Heart Study and Strong Heart Family Study

The ongoing pandemic of Severe Acute Respiratory Syndrome Coronavirus infections has taken a devastating toll on American Indian and Alaskan Native populations with hospitalization and death rate ratios for COVID

Effects of COVID-19 Vaccine Safety Framing on Parental Reactions

Despite the benefits and worldwide approval use of COVID vaccination for children parents still remain a high level of vaccine hesitancy due to concerns about vaccine safety

Regional Variations in Vaccination Against COVID-19 in Germany

In order to curb the SARSCoV virus vaccines were developed as quickly as possible in and enormous vaccination campaigns started by the end of in the industrialized countries In the first months of

Identification of Differentially Expressed mRNA/lncRNA Modules in Acutely Regorafenib-treated Sorafenib-resistant Huh7 Hepatocellular Carcinoma Cells

The multikinase inhibitor sorafenib is the standard firstline treatment for advanced hepatocellular carcinoma but many patients become sorafenibresistant This study investigated the efficacy of another kinase inhibitor

Intelligent Supervision of PIVAS Drug Dispensing Based on Image Recognition Technology

Pharmacy intravenous admixture services is in line with GMP standards according to the characteristics of the drug designed for the operation of the environment by the trained pharmacy technicians

High-dose Oral Thiamine Versus Placebo for Chronic Fatigue in Patients With Primary Biliary Cholangitis: a Crossover Randomized Clinical Trial

Primary biliary cholangitis is a chronic inflammatory immunemediated liver disease ultimately leading to liver fibrosis cirrhosis and endstage liver disease PBC is a rare disease with approximately being women aged between

Biomarker Combination Predicting Imminent Relapse After Discontinuation of Biological Drugs in Patients With Rheumatoid Arthritis in Remission

Patients with rheumatoid arthritis had suffered persistent pain from joint inflammation for a long period culminating in joint deformity and miserable life until the advent of methotrexate Methotrexate showed very good effects in reducing

Antibody Desolvation With Sodium Chloride and Acetonitrile Generates Bioactive Protein Nanoparticles

Around of the FDA approved drugs in were therapeutic proteins and their approval for clinical use has since till accounted for an average of Currently most commercial protein therapeutics are administered intravenously

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