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Research Insights

The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.

Evaluation and enhancement of suspected opioid overdose definitions in emergency medical services data using machine learning with natural language processing

Fatal and nonfatal drug overdoses have evolved into a critical public health crisis with over a increase in the rate of fatal drug overdose since Emergency Medical Services EMS data has advantages

Occupational risk factors for depression and anxiety symptoms: Insights from a large cohort study during and after the SARS-CoV-2 pandemic

An increased risk for an occupationrelated SARSCoV infection has been linked to higher psychological distress This online survey investigates the prevalence of depressive and anxiety symptoms in a large sample

Ultrasound-triggered doxorubicin targeted delivery for liver cancer treatment: Reduced toxicity and improved efficacy

Liver cancer especially hepatocellular carcinoma HCC remains a major global health challenge causing high mortality worldwide Conventional chemotherapy often results in severe side effects due to its systemic distribution

Risk assessment for cardiovascular adverse drug events in the ICU: Case study on COVID-19 patients

The COVID outbreak quickly became a pandemic In Brazil more than seven million cases were recorded in

Topological stratification of continuous genetic variation in large biobanks

Biobanks now contain genetic data from millions of individuals Dimensionality reduction visualization and clustering are standard when exploring data at these scales while efficient and tractable methods exist

Non-immersive virtual reality telerehabilitation for motor accuracy and precision in individuals with Cerebral Palsy: A non-randomized clinical trial

This study aimed to describe motor performance accuracy and precision in individuals with Cerebral Palsy CP compared to typically developing individuals controls and to examine longitudinal changes during a nonimmersive

The Nottingham recovery from COVID-19 research platform (NoRCoRP): Functional, clinical and patient-reported outcomes in adults referred to a post-COVID respiratory service

To characterise symptoms function and patientreported outcome measures PROMs and identify associated factors in adults with persisting respiratory symptoms postCOVID

Predictive divergence in machine learning models for clinical mortality risk: A multicohort study of covid-19 patients

Machine learning ML algorithms are increasingly used in healthcare to support clinical decisionmaking While models with similar

Assessing the biopotency of the rAAV9 vector In Vitro

The potency assay is critical to ensure the effectiveness and consistency of recombinant Adenoassociated Virus AAV gene therapy vectors especially clinicalgrade products AAV serotype AAV

The synergistic interaction between ACE and TMPRSS2 polymorphisms increases the risk of severe COVID-19

Within a few years after the pandemic outbreak several of evidence have found to suggest that the genetic factors influence the severity and mortality rate of COVID