Research Insights
The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.
System Dynamics Model for an Agile Pharmaceutical Supply Chain During COVID‑19 Pandemic in Iran
Nowadays competition is essential in developing industries Due to the intense competitiveness in the pharmaceutical industries governments try to balance competition and economic growth
Single-cell Transcriptomic Analysis Reveals Rich Pituitary–immune Interactions Under Systemic Inflammation
As the master gland of the endocrine system and a key component in the hypothalamuspituitaryadrenal axis the pituitary releases several hormones to regulate numerous physiological functions such as development sexual maturation
Cas9 Degradation in Human Cells Using Phage Anti-CRISPR Proteins
CRISPR arrays contain fragments of DNA that bacteria use as defense against invading nucleic acids RNAguided CRISPRassociated nucleases identify invaders by first binding
Enteric Pharmacokinetics of Monomeric and Multimeric Camelid Nanobody Single-domain Antibodies
Enteric diseases substantially impact health in both human and veterinary medicine While modern sanitation methods largely control enteric disease in the developed world foodborne pathogens remain a major cause of disease
Genome-wide Association Studies on Coronary Artery Disease: a Systematic Review and Implications for Populations of Different Ancestries
We performed a systematic review on the th of October summarizing genomewide association studies on coronary artery disease while employing the GWAS Catalog as an independent database to support the search
Stemness Genes and Mir-1247-3P Expression Associate With Clinicopathological Parameters and Prognosis in Lung Adenocarcinoma
Lung cancer makes up onefourth of all cancerrelated mortality with the highest mortality rate among all cancers Despite recent scientific advancements in cancer therapeutics the year survival rate of lung adenocarcinoma
Investigating the Impact of Physical Activity on Mitochondrial Function in Parkinson’s Disease (PARKEX): Study Protocol for a Randomized Controlled Clinical Trial
Parkinsons disease is a disorder characterized by the progressive degeneration of dopaminergic neurons resulting in a deficiency of dopamine in the striatum in the basal ganglia PD patients experience both motor and nonmotor symptoms
GPC-100, a Novel CXCR4 Antagonist, Improves in Vivo Hematopoietic Cell Mobilization When Combined With Propranolol
Multiple myeloma is a leading hematological malignancy with an estimated cases in the United States and approximately cases worldwide each year Autologous Stem Cell Transplant
RNA-seq RNAaccess Identified as the Preferred Method for Gene Expression Analysis of Low Quality FFPE Samples
Clinical tumor tissues that are preserved as formalinfixed paraffinembedded samples result in extensive crosslinking fragmentation and chemical modification of RNA posing significant challenges for RNAseqbased gene expression profiling
The impact of Gam-COVID-Vac, an Adv5/Adv26 COVID-19 vaccine, on the biomarkers of endothelial function, coagulation and platelet activation
COVID vaccination has occasionally been linked to rare yet severe venous and arterial clotting incidents both with and without a decrease in platelet count
