Research Insights
The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.
Relative expression of microRNAs, apoptosis, and ultrastructure anomalies induced by gold nanoparticles in Trachyderma hispida (Coleoptera: Tenebrionidae)
The extensive use of nanomaterials generates toxic effects on nontarget species and the ecosystem Although gold nanoparticles AuNPs are generally expected to be safe the recent study a
Whole blood transcriptome biomarkers of unruptured intracranial aneurysm
The rupture of an intracranial aneurysm IA causes devastating subarachnoid hemorrhages yet most IAs remain undiscovered until they rupture Recently we found an IA RNA expression signature of circulating neutrophils
The relationship between circulating lipids and breast cancer risk
Numerous epidemiological and genetic studies have investigated the potential link between circulating lipid levels and the risk of various cancers including breast cancer BC
Age at diagnosis, glycemic trajectories, and responses to oral glucose-lowering drugs in type 2 diabetes in Hong Kong
Lifetime glycemic exposure and its relationship with age at diagnosis in type diabetes TD are unknown Pharmacologic glycemic management strategies for youngonset TD age at diagnosis
Enhanced treatment strategies and distinct disease outcomes among autoantibody-positive and -negative rheumatoid arthritis patients over 25 years
Based on different genetic and environmental risk factors and histology it has been proposed that rheumatoid arthritis RA consists of types autoantibodypositive and autoantibodynegative RA However until now this remained hypothetical
Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections
There is disagreement about the level of asymptomatic severe acute respiratory syndrome coronavirus SARSCoV infection We conducted a living systematic review and metaanalysis to address three questions Amongst people who become infected with SARSCoV what proportion does not experience symptoms at all during their infection
Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans
There is growing concern that racial and ethnic minority communities around the world are experiencing a disproportionate burden of severe acute respiratory syndrome coronavirus SARSCoV infection and coronavirus disease COVID
Lymphocytic infiltration in stage II microsatellite stable colorectal tumors
Identifying stage II patients with colorectal cancer CRC at higher risk of progression is a clinical priority in order to optimize the advantages of adjuvant chemotherapy while avoiding unnecessary toxicity
Circulating tumour DNA in metastatic breast cancer to guide clinical trial
Metastatic breast cancer mBC is a heterogenous disease with increasing availability of targeted therapies as well as emerging genomic markers of therapeutic resistance necessitating timely and accurate molecular characterization of disease
Partitioning stable and unstable expression level variation in cell populations: A theoretical framework and its application to the T cell receptor
Phenotypic variation in the copy number of gene products expressed by cells or tissues has been the focus of intense investigation To what extent the observed differences in cellular expression levels
