Research Insights

The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.

Potential synergistic activity of quercetin with antibiotics against multidrug-resistant clinical strains of Pseudomonas aeruginosa

Development of drug resistance in opportunistic pathogens is one of the major healthcare challenges associated with infection management Combination therapy

Global gene network exploration based on explainable artificial intelligence approach

In recent years personalized gene regulatory networks have received significant attention and interpretation of the multilayer networks has been a critical issue

Evaluation of classification and forecasting methods on time series gene expression data

Time series gene expression data is widely used to study different dynamic biological processes Although gene expression datasets share many of the characteristics of time series

Relative expression of microRNAs, apoptosis, and ultrastructure anomalies induced by gold nanoparticles in Trachyderma hispida (Coleoptera: Tenebrionidae)

The extensive use of nanomaterials generates toxic effects on nontarget species and the ecosystem Although gold nanoparticles AuNPs are generally expected to be safe the recent study a

Whole blood transcriptome biomarkers of unruptured intracranial aneurysm

The rupture of an intracranial aneurysm IA causes devastating subarachnoid hemorrhages yet most IAs remain undiscovered until they rupture Recently we found an IA RNA expression signature of circulating neutrophils

The relationship between circulating lipids and breast cancer risk

Numerous epidemiological and genetic studies have investigated the potential link between circulating lipid levels and the risk of various cancers including breast cancer BC

Age at diagnosis, glycemic trajectories, and responses to oral glucose-lowering drugs in type 2 diabetes in Hong Kong

Lifetime glycemic exposure and its relationship with age at diagnosis in type diabetes TD are unknown Pharmacologic glycemic management strategies for youngonset TD age at diagnosis

Enhanced treatment strategies and distinct disease outcomes among autoantibody-positive and -negative rheumatoid arthritis patients over 25 years

Based on different genetic and environmental risk factors and histology it has been proposed that rheumatoid arthritis RA consists of types autoantibodypositive and autoantibodynegative RA However until now this remained hypothetical

Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections

There is disagreement about the level of asymptomatic severe acute respiratory syndrome coronavirus SARSCoV infection We conducted a living systematic review and metaanalysis to address three questions Amongst people who become infected with SARSCoV what proportion does not experience symptoms at all during their infection

Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans

There is growing concern that racial and ethnic minority communities around the world are experiencing a disproportionate burden of severe acute respiratory syndrome coronavirus SARSCoV infection and coronavirus disease COVID