Research Insights
The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.
Self-emulsifying drug delivery systems: A versatile approach to enhance the oral delivery of BCS class III drug via hydrophobic ion pairing
Biopharmaceutical classification systems BCS class III drugs belongs to a group of drugs with high solubility in gastrointestinal GI fluids and low membrane permeability result in significantly low bioavailability
NAV-001, a high-efficacy antibody-drug conjugate targeting mesothelin with improved delivery of a potent payload by counteracting MUC16/CA125 inhibitory effects
Subsets of tumorproduced cell surface and secreted proteins can bind to IgG type antibodies and suppress their immuneeffector activities
A fragment-based drug discovery developed on ciclopirox for inhibition of Hepatitis B virus core protein: An in silico study
The Hepatitis B virus HBV core protein is an attractive target for preventing capsid assembly and viral replication Drug repurposing strategies have introduced several drugs targeting HBV core protein
Vancomycin prescribing and therapeutic drug monitoring: Challenges of real clinical practice
Mariam Hantash Abdel Jalil Rima ijazeenFarah Khaled AbuMahfouzKhawla Abu HammourMaria Hasan MatalqahJwan Saleh Khaleel AlbadainehShrouq Khaled AlOmoushMontaha AlIede
Development and Characterization of a Copolymeric Micelle Containing Soluble and Insoluble Model Drugs
Micelles are nanosized particles with a coreshell structure that are made by natural or synthetic polymers or copolymers
Pbp1 Associates With Puf3 and Promotes Translation of Its Target mRNAs Involved in Mitochondrial Biogenesis
Pbp polyAbinding proteinbinding protein is a cytoplasmic stress granule marker that is capable of forming condensates that function in the negative regulation of TORC signaling under respiratory conditions
Deep Self-supervised Learning for Biosynthetic Gene Cluster Detection and Product Classification
Carolina RiosMartinez Nicholas Bhattacharya Ava P Amini Lorin Crawford Kevin K Yang
Expression of RNA polymerase I catalytic core is influenced by RPA12
Brittany L FordTing Wei Hester Liu Catherine E Scull Saman M Najmi Stephanie Pitts Wenjun Fan David A Schneider Marikki Laiho
RWD-derived response in multiple myeloma
Realworld data RWD are important for understanding the treatment course and response patterns of patients with multiple myeloma
Immunogenicity of a spike protein subunit-based COVID-19 vaccine with broad protection against various SARS-CoV-2 variants in animal studies
SARSCoV pandemic has profound impacts on human life and global economy since the outbreak in
