Research Insights
The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.
FARE-CAFE: a database of functional and regulatory elements of cancer-associated fusion events
Abstract Chromosomal translocation CT is of enormous clinical interest because this disorder is associated with various major solid tumors and leukemia A tumorspecific fusion gene event may occur when a translocation joins two separate genes Currently various CT databases provide information about fusion genes and their genomic elements However no...
Analytical and statistical comparability of generic enoxaparins from the US market with the originator product
Lowmolecularweight heparins LMWHs are complex anticoagulant drugs made from heparin porcine mucosa starting material Enoxaparin sodium manufactured by Sanofi is one of the most widely prescribed LMWHs
Peptides and Peptidomimetics for Antimicrobial Drug Design
The purpose of this paper is to introduce and highlight a few classes of traditional antimicrobial peptides
Use of Fixed Dose Combination (FDC) Drugs in India: Central Regulatory Approval and Sales of FDCs Containing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Metformin, or Psychotropic Drugs
In a committee in the Indian parliament revealed that state authorities had issued manufacturing licenses for numerous fixed dose combination FDC drugs without prior approval from the Central Drugs Standard Control Organization
Analytical Quality by Design: A Tool for Regulatory Flexibility and Robust Analytics
Very recently Food and Drug Administration FDA has approved a few new drug applications NDA with regulatory flexibility for quality by design QbD based analytical approach
An Empirical Analysis of Primary and Secondary Pharmaceutical Patents in Chile
In our study we examine the patent filing practices of foreign pharmaceutical companies in Chile specifically distinguishing between primary patents related to the active ingredient and secondary patents
Defining the In Vivo Phenotype of Artemisinin-Resistant Falciparum Malaria: A Modelling Approach
The analysis involved data from patients residing on the ThaiMyanmar and ThaiCambodian borders who underwent artesunate treatment with parasite halflife assessments conducted
Integrity testing of Planova™ BioEX virus removal filters used in the manufacture of biological products
Ensuring the integrity of virus filters is crucial for the safety of biological products There are two main types of defects that can affect virus filter performance improper poresize distribution and specific
Complaints, Complainants, and Rulings Regarding Drug Promotion in the United Kingdom and Sweden 2004–2012: A Quantitative and Qualitative Study of Pharmaceutical Industry Self-Regulation
In many European countries medicines promotion is governed by voluntary codes of practice administered by the pharmaceutical industry under its own system of selfregulation
Synthetic Biodegradable Polymers Used in Controlled Drug Delivery System: An Overview
Polymers are becoming increasingly important in the field of drug delivery The pharmaceutical applications of polymers range from their use as binders in tablets to viscosity and flow controlling agents in liquids
