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Research Insights

The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.

The effect of pharmaceutical care in the elderly patients with type 2 diabetes mellitus

Keywords Pharmaceutical care Type diabetes mellitus Quality of life Clinical outcomes Pharmaceutical care plays a crucial role in reducing mortality and morbidities of the patients A hospital based quasiexperimental study was conducted with elderly patients with type diabetes who attended at the diabetes clinic of No M

The effects of shifting tasks from pharmacy to non-pharmacy personnel for providing antiretroviral therapy to people living with HIV: a systematic review protocol

Shifting selected antiretroviral therapy ART tasks from specialised healthcare workers to those with shorter or less formal training has been implemented in resourcelimited settings to alleviate critical shortages

Development and validation of an instrument to assess treatment adherence for each individual drug taken by a patient

The development of the instrument involved conducting a comprehensive literature search and conducting interviews with experts in the field Pilot testing was performed with patients to assess clarity and wording

Pharmaceuticals and the Environment (PiE): Evolution and impact of the published literature revealed by bibliometric analysis

Abstract The evolution and impact of the published literature surrounding the transdisciplinary multifaceted topic of pharmaceuticals as contaminants in the environment is examined for the first time in an historical context The preponderance of literature cited in this examination represents the earlier works As an historical chronology the focus...

Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain

Phosphodiesterases PDEs are enzymes that play a crucial role in cellular signaling by breaking down the secondary messengers cyclic adenosine monophosphate cAMP andor cyclic guanosine monophosphate cGMP in the body and brain

Evaluation of dose-efficacy of sorafenib and effect of transarterial chemoembolization in hepatocellular carcinoma patients: a retrospective study

Transarterial chemoembolization TACE and sorafenib are the therapeutic standard for intermediate and advanced stage hepatocellular carcinoma HCC patients respectively High costs with adverse events AE of sorafenib might limit sorafenib dosage

Identifying Viable Regulatory and Innovation Pathways for Regenerative Medicine

The development of red blood cells for the blood transfusion market is a groundbreaking advancement in regenerative medicine This article explores a research project that aims to produce red blood cells from human embryonic stem cells

Using Residence Time Distributions (RTDs) to Address the Traceability of Raw Materials in Continuous Pharmaceutical Manufacturing

Abstract Continuous processing in pharmaceutical manufacturing is a relatively new approach that has generated significant attention While it has been used for decades in other industries showing significant advantages the pharmaceutical industry has been slow in its adoption of continuous processing primarily due to regulatory uncertainty This pa...

Utilization of an Eilat Virus-Based Chimera for Serological Detection of Chikungunya Infection

Abstract In December of chikungunya virus CHIKV an alphavirus in the family Togaviridae was introduced to the island of Saint Martin in the Caribbean resulting in the first autochthonous cases reported in the Americas As of January local and imported CHIKV has been reported in American countries with over million suspected cases CHIKV c

FARE-CAFE: a database of functional and regulatory elements of cancer-associated fusion events

Abstract Chromosomal translocation CT is of enormous clinical interest because this disorder is associated with various major solid tumors and leukemia A tumorspecific fusion gene event may occur when a translocation joins two separate genes Currently various CT databases provide information about fusion genes and their genomic elements However no...