Research Insights
The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.
Analytical methods for determination of terbinafine hydrochloride in pharmaceuticals and biological materials
Abstract Terbinafine is a new powerful antifungal agent indicated for both oral and topical treatment of mycosessince It is highly effective in the treatment of determatomycoses The chemical and pharmaceutical analysis of the drug requires effective analytical methods for quality control and pharmacodynamic and pharmacokinetic studies Ever since i...
Knowledge integration using product R&D outsourcing in biotechnology
We build on systems integration literature to explain how and why knowledge integration of nonmodular products is based on a strategic choice between internalizing and outsourcing core RD
Role of sTREM-1 in predicting mortality of infection: a systematic review and meta-analysis
The aim of this metaanalysis was to assess the prognostic value of soluble triggering receptor expressed on myeloid cells sTREM levels in predicting mortality during the initial stage of infection
The model beetle Tribolium castaneum can be used as an early warning system for transgenerational epigenetic side effects caused by pharmaceuticals
Currently pharmaceuticals undergo limited testing for transgenerational and epigenetic side effects The utilization of vertebrates as preclinical research models is hindered by their lengthy generation times
What do pharmaceutical industry professionals in Europe believe about involving patients and the public in research and development of medicines? A qualitative interview study
Abstract Objectives To explore Europeanbased pharmaceutical industry professionals beliefs about patient and public involvement PPI in medicines research and development RD Setting Pharmaceutical companies in the UK Poland and Spain
Mixed-mode chromatography in pharmaceutical and biopharmaceutical applications
Abstract Mixedmode chromatography MMC is a fast growing area in recent years thanks to the new generation of mixedmode stationary phases and better understanding of multimode interactions MMC has superior applications in the separation of compounds that are not retained or not well resolved by typical reversedphase LC methods especially for polar...
Biosensor-based engineering of biosynthetic pathways
Biosynthetic pathways offer an enzymatic pathway for transforming inexpensive renewable resources into valuable metabolic products like pharmaceuticals and plastics However designing these pathways
Improving the management of multimorbidity in general practice: protocol of a cluster randomised controlled trial (The 3D Study)
An increasing number of people are living with multimorbidity The evidence base for how best to manage these patients is weak Current clinical guidelines generally focus on single conditions
Pharmaceutical treatments to prevent recurrence of endometriosis following surgery: a model-based economic evaluation
Conduct an economic evaluation based on best currently available evidence comparing alternative treatments levonorgestrelreleasing intrauterine system depotmedroxyprogesterone acetate combined oral contraceptive pill
Trends in clinical development timeframes for antiviral drugs launched in the UK, 1981–2014: a retrospective observational study
Recent decades have witnessed the development of highly innovative new antiviral drug therapies However there are concerns that rising costs and lengthening development times could have implications
