Research Insights
The Research Insights section focuses on the latest breakthroughs in medicine and science, as well as the laboratory works around the world. Research insights directly from these labs add tremendous value to our readers.
Recreational Drug Use In The Oslo Nightlife Setting: Study Protocol For A Cross-Sectional Time Series Using Biological Markers, Self-Reported And Qualitative Data
Introduction Recreational drug use in the nightlife setting carries the risk of many negative consequences such as violence injuries aberrant driving and sexual risktaking
Review On Potential Phytocompounds In Drug Development For Parkinson Disease: A Pharmacoinformatic Approach
Abstract Parkinsons disease PD is caused by human physiological function and is ranked as the second most common neurodegenerative disorder One of the prominent therapies currently available for PD is the use of dopamine agonists which mimic the natural action of dopamine in the brain and stimulate dopamine receptors directly Currently available p...
Spectrophotometric And Spectroscopic Studies On Charge Transfer Complexes Of Antifungal Drug Clotrimazole
Clotrimazole CLZ is an imidazole derivative which is therapeutically used as an antifungal drug The routine control analysis of CLZ requires rapid reliable accurate and precise methods for the quantification
Analytical Methods For Determination Of Terbinafine Hydrochloride In Pharmaceuticals And Biological Materials
Abstract Terbinafine is a new powerful antifungal agent indicated for both oral and topical treatment of mycosessince It is highly effective in the treatment of determatomycoses The chemical and pharmaceutical analysis of the drug requires effective analytical methods for quality control and pharmacodynamic and pharmacokinetic studies Ever since i...
Renal Drug Transporters And Their Significance In Drug–drug Interactions
Abstract The kidney is a vital organ for the elimination of therapeutic drugs and their metabolites Renal drug transporters which are primarily located in the renal proximal tubules play an important role in tubular secretion and reabsorption of drug molecules in the kidney Tubular secretion is characterized by high clearance capacities broad subs...
Effectiveness Of A Novel Cellular Therapy To Treat Multidrug-resistant Tuberculosis
We urgently need novel treatments for multidrugresistant tuberculosis MDRTB Autologous mesenchymal stromal cell MSC infusion is one such possibility due to its potential to repair
Evaluation Of Ion Exchange Processes In Drug-eluting Embolization Beads By Use Of An Improved Flow-through Elution Method
Abstract An improved method for evaluating drug release behaviour of drugeluting embolization beads DEBs was developed utilizing an openloop flowthrough system in which the beads were packed into an occlusive mass within the system and extracted with a flowing elution medium over time Glass beads were introduced into the beads mass in order to ens...
Spectrophotometric determination of Ethionamide in Pharmaceuticals using Folin-Ciocalteu reagent and Iron (III)-Ferricyanide as Chromogenic Agents
ETM in a sodium carbonate medium resulting in the formation of a bluecolored complex that can be measured at nm referred to as the Molybdenumtungsten blue method The second method known as the Prussian blue method
Discrete Event Simulation Modelling For Dynamic Decision Making In Biopharmaceutical Manufacturing
Abstract With the increase in demand for biopharmaceutical products industries have realised the need to scale up their manufacturing from laboratorybased processes to financially viable production processes In this context biopharmaceutical manufacturers are increasingly using simulationbased approaches to gain transparency of their current produ...
Antitubercular Drugs For An Old Target: GSK693 As A Promising InhA Direct Inhibitor
Isoniazid INH has long been a key drug in the treatment of tuberculosis TB but the emergence of resistance poses a significant challenge Resistance to INH is often associated with mutations in the enzyme KatG
