Synthetic Biodegradable Polymers Used in Controlled Drug Delivery System: An Overview
Amit Jagannath Gavasane and Harshal Ashok Pawar
Abstract
Polymers play an increasingly vital role in drug delivery, offering a wide range of pharmaceutical applications. They serve as binders in tablets and regulate viscosity and flow in liquids, suspensions, and emulsions. Moreover, polymers are now utilized in controlled release and targeted drug delivery systems. These versatile materials can be derived from natural sources or chemically synthesized. They are classified as either biodegradable or nonbiodegradable, with biodegradable polymers being extensively employed in biomedical applications due to their biocompatibility and biodegradability. This review provides an overview of various biodegradable polymers currently employed in the development of controlled drug delivery systems.
Conclusion: Polymers possess unique attributes that enable significant advancements in drug delivery systems, thereby enhancing therapy and treatment. Biodegradable polymers have demonstrated immense potential for the development of efficient and advanced drug delivery systems, capable of delivering a wide range of bioactive substances. Considering polymer chemistry, it is crucial to acknowledge the importance of physico-chemical properties in achieving controlled release mechanisms. Numerous types of polymers, including nanoparticles, micro-particles, dendrimers, micro-spheres, capsosomes, and micelles, have been investigated as potential drug delivery systems. These systems enable the encapsulation or conjugation of drugs within polymer matrices to achieve controlled drug release.
Citation: Gavasane AJ, Pawar HA (2014) Synthetic Biodegradable Polymers Used in Controlled Drug Delivery System: An Overview. Clin Pharmacol Biopharm 3:121.doi: 10.4172/2167-065X.1000121
Received: September 08, 2014; Accepted: September 18, 2014; Published: September 22, 2014
Copyright: 2014 Gavasane AJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Acknowledgments:
Authors are very much thankful to Dr. P. S. Gide, Principal, Hyderabad (Sindh) National Collegiate Board’s Dr. L.H.Hiranandani college of pharmacy, Ulhasnagar for his continuous support, guidance and encouragement.
Conflict of Interests: The author(s) declare(s) that there is no conflict of interests regarding the publication of this article.
