EDITORIAL SECTION

Articles

Manufacturing mRNA, Cell, and Gene Therapies at Commercial Scale

Why Cell and Gene Therapies Fail in Europe After the Science Has Already Worked The uncomfortable statistic for anyone financing advanced therapies in Europe is not the clinical attrition rate It is the withdrawal rate after approval An analysis of advanced therapy medicinal products granted European marketing authorisation found that roughly one in five had subsequently been withdrawn and of th...

Medical Devices and Pharma: A Symbiotic Relationship for Improved Healthcare

The healthcare industry is continually evolving driven by technological advancements and innovative approaches to patient care Among the most significant developments is the symbiotic relationship between medical devices

Innovative Solutions: Cell and Gene Therapy's Impact on Pharma

Cell therapy involves the use of living cells to treat medical conditions These cells can be sourced from a patient or a donor and are often manipulated or engineered to enhance their therapeutic effects

Brain Delivery of Biologics with Trojan Horse Shuttles: Remembering Paracelsus

Paracelsus in the th century established the principle of toxicology that the dose of a medicinal defines the difference between a remedy and a toxic effect

Navigating the Pharma Market: Strategies for Successful Pharmaceutical Sales

Navigating the pharmaceutical market requires a blend of strategic planning industry knowledge and effective communication skills In this guide well explore key strategies for successful pharmaceutical sales in a way thats easy to understand

The Integration of Genomics into European Drug Development: Advances and Implications

Genomics in which genes and their novelty are discovered and taken into account as tools has recently risen as a strong tool in the drug discovery process Applying genomics into drug development in Europe has therefore provided a way towards more effective and safer drugs In light of the present analysis this article addresses how genomics is transforming drug development in Europe and its benefit...

Techno Trends

University of Queensland Researchers Unlock New Drug Target for Neurodegenerative Disease Therapies

University of Queensland UQ researchers have developed a novel drug molecule that targets the hardtostudy immune receptor CaR opening new possibilities for treatments targeting neurodegenerative diseases such as Motor Neurone Disease MND

Projects

Evonik Announces US$100 Million Modernization of U.S. Drug Substance CDMO Facility

Evonik has announced a US million investment to modernize its Tippecanoe Labs manufacturing site in Lafayette Indiana over the next five years The investment is aimed at strengthening the companys US drug substance

Research Insights

A genomic-led strategy to anticipate drug safety effects

Safetyrelated issues account for approximately of failures in new drug discovery programs On top of that many are discovered during postmarketing surveillance

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys