EDITORIAL SECTION

Articles

Innovative Pricing Models in the EU: Making Medicines Affordable for All

Pricing policies are important determinants in delivering sufficiently cheap medicines in all the member nations of the EU High costs of meeting the required medical care together with arising independent differentiated technological improvements have rendered exhausted pricing structures as uncompetitive tools for fairness New mechanisms of pricing have been introduced

Exploring the Versatility of Using 3D Spheroid Models in Research

Cell culture technology forms the foundation of modern biological and pharmaceutical research For many years twodimensional culture systems have served as standard experimental models for studying cellular behavior disease mechanisms and therapeutic responses Although these models contribute significantly to scientific discovery they cannot fully replicate the structural and functional complexity...

Assessing the Impact of Tariffs on the Pharmaceutical Industry

The pharmaceutical industry function as a vital foundation for worldwide healthcare infrastructure because they push medical advancement while supporting medication availability to patients The pharmaceutical industry deals with major operational obstacles when public authorities establish tariffs for both pharmaceutical imports and exports The implementation of tariffs affects how prices shift wh...

Cell and Gene Therapy's Trillion-Dollar Reckoning Is Here

Cell and gene therapies can cure diseases once thought untreatable Yet a string of commercial collapses now suggests that curing the patient and sustaining the business are two very different challenges and the industry is confronting the gap at last

The Impact of AI and Machine Learning on Drug Discovery

Now and then an industry hits a point where the old ways no matter how trusted start to feel a bit like trying to run a marathon in hiking boots Drug discovery is in that spot For decades pharmaceutical RD leaned heavily on long painstaking experiments and the occasional stroke of luck Entire teams would spend years nudging molecules around waiting for a hint that something might work After all th...

From Lab to Market: The Journey of a New Drug

The process of synthesizing a new drug takes many years and several phases and all of them are important for the drug safety and efficacy Which from the first identification in a lab to the final approval of use by the public is a process that takes over years and this involves work done by scientists various agencies and other health care givers

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys