EDITORIAL SECTION

Articles

Ritonavir: How the Discovery of a New Polymorph Changed Drug Development Forever

AIDS is a chronic illness that gained global attention in the s It weakens the immune system of the body making it hard to fight infections When HIV enters the body it targets CD Tcells a type of white blood cell that helps defend against diseases It uses the machinery of Tcells to make new copies of the virus due to which the immune cells are destroyed As the virus spreads and the number of healt...

Biosimilars in Europe: Expanding Access and Reducing Costs

The use of biosimilars as a part of modern health care systems is also fairly important especially in the context of the European Union as they can enhance the availability of the required treatments and reduce the costs of the health care sector As biologic medicines are recognized as firstline treatments for critical illnesses such as cancer autoimmune diseases and rheumatoid arthritis biosimila...

How Drug Patents Shape the Competitive Landscape in Pharma?

It can rightly be said that the business of pharmaceuticals is very sensitive and crucial since business is all about the manufacturing of change for the purpose of ridding the world of diseases

The Next Growth Strategy: Scaling GLP-1 Manufacturing and Global Market Expansion

For most of the past four years the strategic conversation around GLP receptor agonists was a demand story Prescriptions outran forecasts waiting lists formed pharmacy shelves emptied and the commercial debate centred on reimbursement prescriber behaviour and how far the obesity indication could stretch That conversation has changed Demand for incretin therapies is now the most predictable variabl...

The Architect of the Void: When 3D Printing Becomes the Body’s New Bone

In the quiet pressurised hum of a modern surgical suite a surgeon holds a highdefinition scan of a young patients femur On the screen a jagged dark shadow marks where an osteosarcoma has claimed its territory For decades the script for this moment has been written in cold hard steel

Global CDMO Expansion: Supporting the Growing Advanced Therapy Pipeline

The European advanced therapy sector has spent the better part of two decades proving a scientific point that engineered cells corrected genes and reprogrammed immune systems can deliver durable clinical benefit That argument is now largely settled The question facing pharmaceutical and biotech leadership is industrial rather than scientific whether these therapies can be manufactured consistentl...

Techno Trends

Juniper Biosciences Secures FDA Breakthrough Designation

The US Food and Drug Administration FDA has granted Breakthrough Therapy Designation to Juniper Biosciences JBS Ffluoromisonidazole or FMISO for identifying tumour hypoxia in patients with HPVpositive oropharyngeal carcinoma OPC

Projects

Onyx Scientific to Invest Over US$2 Million (£1.5 Million) in Sunderland GMP Facility Expansion

Onyx Scientific is investing more than US Million Million to expand its Good Manufacturing Practice GMP facilities at its Sunderland UK site The investment will increase capacity for commercial

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys