EDITORIAL SECTION

Articles

The Future of Pharma and CRO Operations: A Practical Guide to Automation

Many pharmaceutical leaders assume productivity gains will come from copilots conversational tools that help staff draft text or find information faster Yet copilots remain confined to the surface of work They assist with isolated tasks but cannot follow a process through to completion They do not manage clinical operations budgets or respond to RFPs for instance

The Role of Automation in Pharmaceutical Manufacturing

Modern pharmaceutics gained momentum through technological progress which primarily involved automation in pharmaceutical production processes The drug development process now produces major changes in drug manufacturing pipeline operations from start to finish delivery to marketplaces The pharmaceutical industry requires better efficiency together with precision and speed and therefore automation...

Why Leading Pharma Professionals Rely on the Pharma Focus Europe E-Newsletter

The network of the pharmaceutical and life sciences in Europe is undergoing a radical transformation There are changes in the regulatory environments a rise in the pace of innovation a shift in leadership and a change in the distribution production and development of therapies by the use of digital technologies In this environment no longer will access to timely credible and context rich informati...

The Cost of Uncertainty: How Analytical Chemistry Drives Billion-Dollar Decisions in Pharma

In pharmaceutical development uncertainty is not an abstract scientific inconvenience It has a cost a timeline a regulatory consequence and ultimately a patient impact A promising medicine may have strong biological rationale compelling early data and significant commercial potential yet still face a fundamental question do we truly understand the product well enough to develop manufacture approve...

Gene Therapy: Breakthrough Treatments for Rare Diseases

The idea of gene therapy is radically changing the sphere of medicine with the possibilities to cure the patients with the rare hereditary diseases These diseases which are usually brought about by the alteration of the sequence

Ethical Standards and Responsible Decision-Making in the Pharmaceutical Industry

Picture this a new drug hits the market promising relief for millions But behind that promise lies a web of decisions about pricing clinical trial design marketing claims and data transparency

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys