EDITORIAL SECTION

Articles

A Closer Look at Pharmacological Interventions: Treatment Overview

Pharmacological interventions are a cornerstone of modern healthcare encompassing a diverse array of medications designed to treat alleviate or prevent various medical conditions

The Next Growth Strategy: Scaling GLP-1 Manufacturing and Global Market Expansion

For most of the past four years the strategic conversation around GLP receptor agonists was a demand story Prescriptions outran forecasts waiting lists formed pharmacy shelves emptied and the commercial debate centred on reimbursement prescriber behaviour and how far the obesity indication could stretch That conversation has changed Demand for incretin therapies is now the most predictable variabl...

Considerations and Functional Elements of Closed Systems: Isolators and Single Use Systems

Advances in technology have demonstrated the feasibility of using isolators and singleuse systems SUS in routine pharmaceutical manufacturing operations particularly in aseptic processing Their implementation has significantly reduced the risk of chemical particulate and microbiological contamination

The Role of Technology in Enhancing Patient Acceptance and Satisfaction

Technology has revolutionized every aspect of our lives and healthcare is no exception From electronic health records EHRs to telemedicine and wearable devices advancements in technology

Navigating European Pharma Regulations: A B2B Perspective

The pharmaceutical industry in the European region practices one of the most regulating laws in the entire world Therefore regulations encompassing these areas are of prime importance for BB companies that need to achieve market entry and maintain compliance Thus this guide is meant to decompartmentalize the array of European pharma regulations and create

Why AI Is Changing What Good Validation Looks Like

The comprehensive landmark report and framework set out seven principles for using AI safely in pharmacovigilance together advocating a riskbased approach to governance validation and more Here ArisGlobals Jason Bryant highlights some of the guidances main assumptions as recently distilled in a podcast with Denny Lorenz a core member of the CIOMS XIV working group

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys