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Articles

Fostering Pharma Collaboration: Challenges & Opportunities

In the everevolving world of pharmaceuticals fostering collaboration is essential for driving innovation and meeting the diverse needs of patients However this seemingly simple goal is often hindered by numerous challenges

Antibody-Drug Conjugates (ADCs): Driving the Next Generation of Precision Oncology

An antibodydrug conjugate is a targeted cancer therapy that links a potent cytotoxic drug to a monoclonal antibody through a chemical linker so the antibody delivers the payload directly to tumour cells expressing a chosen antigen The design widens the therapeutic window it concentrates cytotoxic activity where the target is expressed and limits the systemic exposure that constrains conventional c...

Precision Oncology Trials: Navigating the Future of Cancer Care

Precision oncology is revolutionizing cancer care offering targeted treatments tailored to each patients unique genetic makeup As we navigate the future of cancer care precision oncology trials are paving the way for more effective and personalized treatment options

Pharmaceutical Serialization in Europe: Ensuring Safety in the Supply Chain

Over the past few years however Europes pharmaceutical companies have faced a rather challenging role of fighting counterfeiting of medicines and therefore their patients Serialization it is a system that uses a special code assigned to every product has become one of the salient solutions to tackle counterfeit drugs While serialization in terms

Global CDMO Expansion: Supporting the Growing Advanced Therapy Pipeline

The European advanced therapy sector has spent the better part of two decades proving a scientific point that engineered cells corrected genes and reprogrammed immune systems can deliver durable clinical benefit That argument is now largely settled The question facing pharmaceutical and biotech leadership is industrial rather than scientific whether these therapies can be manufactured consistentl...

Ethical Standards and Responsible Decision-Making in the Pharmaceutical Industry

Picture this a new drug hits the market promising relief for millions But behind that promise lies a web of decisions about pricing clinical trial design marketing claims and data transparency

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys