EDITORIAL SECTION

Articles

Pharmaceutical Marketing in the Digital Age: Strategies and Challenges

Currently there is a great advancement in the use of technological solutions particularly under the modern pharma digital era Therefore with increase in knowledge dissemination through internet among the citizenry due to enhanced technology

Role of Excipients in Drug Formulation: Functions, Types, and Applications

Whenever we consider medicines we tend to immediately jump into thinking about the active pharmaceutical ingredients APIs the substances that have therapeutic effects However APIs are not enough to develop stable effective and patientfriendly medicines This is where pharmaceutical excipients would come in The importance of excipients in the case of pharmaceuticals can go well beyond the level

Emerging Therapies in Oncology: Advances beyond Traditional Chemotherapy

Cancer formerly was treated by traditional chemotherapy which is a process that employs the use of powerful drugs to eliminate spreading cancer cells Chemotherapy has been a standard for cancer treatment

Bridging the Biotech–Pharma Innovation Gap Through Strategic Partnerships

Europe has never lacked ideas Its universities translational institutes and spinout companies consistently generate novel biology from geneediting tools to antibody engineering and mRNA platforms What the continent has struggled with is the journey that follows turning a validated mechanism into an approved reimbursed and reliably manufactured medicine That journey demands capital regulatory fluen...

Adaptive Trial Designs: Enhancing Speed and Decision-Making in Clinical Development

For decades the traditional clinical trial has followed a rigid script A protocol is written patients are enrolled the study runs to completion and only at the very end does the sponsor learn whether the investment paid off The model has served the industry well in terms of scientific rigour

The New CDMO Strategy: Capacity Expansion for Advanced Therapies

Advanced therapies have moved from scientific curiosity to commercial obligation and the pharmaceutical outsourcing sector is rebuilding itself around that shift This article examines why capacity expansion strategy is migrating from cleanroom square metres towards modularity

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys