EDITORIAL SECTION

Articles

Biosimilars in Europe: Expanding Access and Reducing Costs

The use of biosimilars as a part of modern health care systems is also fairly important especially in the context of the European Union as they can enhance the availability of the required treatments and reduce the costs of the health care sector As biologic medicines are recognized as firstline treatments for critical illnesses such as cancer autoimmune diseases and rheumatoid arthritis biosimila...

mRNA Technology: Unlocking New Possibilities In Therapeutics Beyond Vaccines

In the last few years the mRNA has emerged as a discovery of the century in what concerns biotechnology and medicine Although it has emerged on the global level during the search for COVID vaccines it is used in many other ways Scientists and big pharmacy companies are now investigating virtually all possible uses of mRNA from highly targeted treatments to diseases that had no cure before

AI Governance in Pharma: Managing Trust, Transparency, and Regulatory Expectations

Most large pharmaceutical organisations no longer have an AI strategy problem They have an AI accountability problem Models now sit inside pharmacovigilance case intake deviation triage visual inspection trial feasibility medical information and commercial targeting deployed by different functions on different platforms under different assumptions about who signs

Clinical Trials: Failures and Challenges on the Path to Treating Alzheimer’s

Alzheimers disease AD is a neurodegenerative disorder with symptoms of memory loss and cognitive disability Typically it begins with mild symptoms that progress to become more severe AD is the th leading cause of death in the United States among people or older In million Americans suffered from AD and this is expected to rise to million by

From Digital Transformation to Intelligent Pharma: How AI Is Reshaping Pharmaceutical Strategy

Pharmas digital transformation has solved one problem well access to information Market signals arrive continuously Commercial teams generate customer and channel data medical and scientific functions accumulate new evidence and supply and finance teams produce operational signals that enterprise platforms can now connect across what were once separate systems

The Rise of Bioprinting: Opportunities and Challenges for Personalized Sterile Dosage Forms

Personalized medicine also known as precision medicine has gained significant traction in recent years transforming the healthcare landscape By considering an individuals unique genetic molecular and environmental factors personalized medicine aims to provide targeted therapies that maximize treatment effectiveness while minimizing adverse effects This approach

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys