EDITORIAL SECTION

Articles

Bispecific Antibodies: Transforming the Future of Oncology

For two decades bispecific antibodies occupied an awkward position in pharmaceutical oncology strategy scientifically compelling commercially unproven and persistently difficult to manufacture That characterisation no longer holds Nineteen bispecific antibodies have been approved globally and combined sales of the class passed twelve billion dollars in with several products now anchoring

Advanced Robotics and Autonomous Operations in Pharma Production

Walk the production floor of almost any modern European pharmaceutical site and you will find robots already at work Sixaxis arms denest syringe tubs Gantries load and unload lyophilisers Autonomous mobile units ferry pallets between the warehouse and the dispensary Robotics arrived in pharmaceutical manufacturing more than two decades ago and in the purely mechanical sense the argument was won lo...

Quantum Dot: The Future of Personalized Medicine

Cancer is amongst the most significant health hazards around the globe Individualized chemotherapy offers promise for the forthcoming cancer therapy in clinical practice with each patient receiving tailored medication based on essential biological aspects of a specific tumor One of the most pressing issues is the development of innovative ways for personalized

How M&A Is Reshaping Europe’s Pharmaceutical Pipeline

For most of the past halfcentury a European drugmakers future was written in its own laboratories That model has not disappeared but it has been joined and in many boardrooms overtaken by a second engine of growth the acquisition of externally discovered science

Pharmaceutical Marketing in the Digital Age: Strategies and Challenges

Currently there is a great advancement in the use of technological solutions particularly under the modern pharma digital era Therefore with increase in knowledge dissemination through internet among the citizenry due to enhanced technology

The FDA May Be Coming Unannounced to Your Facility: Are You Ready?

On May the President of the United States signed an executive order with far reaching impact on several agencies including the FDA Among other directives beginning in August the US Food and Drug Administration FDA will initiate unannounced inspections at nonUS manufacturing facilities involved in producing drugs biologics medical devices and diagnostics intended for American consumers and patie...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys