EDITORIAL SECTION

Articles

Digital Biomarkers and Wearables: Transforming Clinical Trial Data Collection

A participant enrolled in a week pharmaceutical trial may spend fewer than six hours inside a clinical site The remaining odd hours of that year the stairs the fatigue the broken nights the good days and the collapsed ones pass unrecorded Clinical development has quietly accepted this trade for decades building enormous capital decisions on a handful of supervised snapshots taken under artificia...

The Cost of Uncertainty: How Analytical Chemistry Drives Billion-Dollar Decisions in Pharma

In pharmaceutical development uncertainty is not an abstract scientific inconvenience It has a cost a timeline a regulatory consequence and ultimately a patient impact A promising medicine may have strong biological rationale compelling early data and significant commercial potential yet still face a fundamental question do we truly understand the product well enough to develop manufacture approve...

Fundamentals of Pharmaceutical Formulation Development

The process of changing an active drug substance into a safe and effective drug is much more complicated than it seems at first sight The core of this undertaking is pharmaceutical formulation development a science and strategic field that unites the pursuit of striking a scientific breakthrough and patient care Even the most promising drug molecule would not confer therapeutic benefits without be...

How Good Clinical Practice (GCP) Compliance Shapes Pharma Success?

Good Clinical Practice GCP compliance is a cornerstone of pharmaceutical research and development ensuring that clinical trials are conducted ethically with participant safety as the top priority

Unleashing the Power of Antimicrobial Peptide Databases: A New Frontier against Antibiotic Resistance

As pathogens continue to evolve and resistance strategies become more sophisticated new solutions are very crucial

Pharma Email Marketing Europe: Personalized Campaigns for C-Suite Leads

The pharmaceutical industry is a very competitive industry and to reach the decisionmakers a focused and strategic marketing strategy is necessary Conventional marketing is not often precise enough to reach executives that drive buying alliances and strategic relationships Here the pharma email marketing has come to play as a potent instrument of relationship establishment with the key stakeholder...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys