EDITORIAL SECTION

Articles

Trapicolast Emerges as a First-In-Class Response to Drug Resistance: The Weakest

Malaria remains one of the worlds most persistent infectious diseases Each year it infects hundreds of millions and causes more than half a million deaths with subSaharan Africa bearing the overwhelming burden Children under five account for most fatalities highlighting malarias deep inequity

The Synergy of Bioinformatics and Computational Biology in Genome Analysis

In the dynamic field of biological sciences the fusion of bioinformatics and computational biology has catalyzed a paradigm shift in genome analysis This synergistic collaboration harnesses cuttingedge computational tools statistical models

Fundamentals of Pharmaceutical Formulation Development

The process of changing an active drug substance into a safe and effective drug is much more complicated than it seems at first sight The core of this undertaking is pharmaceutical formulation development a science and strategic field that unites the pursuit of striking a scientific breakthrough and patient care Even the most promising drug molecule would not confer therapeutic benefits without be...

Regulatory Challenges in Clinical Testing for New Pharmaceuticals

The clinical testing is a stage where the new pharmaceutical products are a trial on human beings or patients The aims of clinical trials are to assess the effectivenesssafetytolerability or intolerance of new drug in man Generally clinical trials are conducted in phases each phase has different questions regarding the drug

Role of QSAR in filling in the gaps of CoVID-19 Therapeutics

Since initial reports from Wuhan China in December and the subsequent declaration of a global pandemic by the WHO in March CoVID has precipitated the greatest health crisis in modern history While exposing fundamental weaknesses in healthcare systems across the globe this tragedy has also been an opportunity for scientists and researchers in different fields to collaborate and produce solutions...

From Visibility to Decision Readiness: The Next Phase of Quality Maturity in Pharma

Over the past decade pharmaceutical organisations have made strong progress in both digitising and digitalising quality operations Systems such as laboratory information management systems LIMS manufacturing execution systems MES and electronic quality management systems eQMS have strengthened traceability embedded workflows and enabled real time visibility across quality processes

Techno Trends

FDA Grants Breakthrough Therapy Designation to Calico's Fosigotifator

Calico Life Sciences LLC has announced that the US Food and Drug Administration FDA has granted Breakthrough Therapy Designation to fosigotifator for the treatment of Vanishing White Matter disease a rare and progressive neurological disorder with no approved therapies

Projects

Johnson & Johnson Invests $1B to Expand U.S. Vision Manufacturing & Distribution

Johnson Johnson has announced an investment of more than billion to expand its Vision manufacturing operations in Jacksonville Florida The project is designed to increase domestic manufacturing packaging and distribution capacity for the company

Research Insights

A genomic-led strategy to anticipate drug safety effects

Safetyrelated issues account for approximately of failures in new drug discovery programs On top of that many are discovered during postmarketing surveillance

whitepaper

Placing the Right Bets: Defining Tailored Investment Strategies for Pharma Launch

Pharmaceutical launches have become significantly harder to execute successfully As IQVIAs new white paper highlights median six month cumulative sales for innovative launches have declined by compared with pre levels reflecting shrinking market opportunities