EDITORIAL SECTION

Articles

Exploring the Benefits of Bioassay in Pharmacology

Pharmacology the study of drugs and their effects on living organisms is a multifaceted field crucial to the development and improvement of pharmaceuticals Bioassay a method that assesses the potency of substances

Understanding Pharmacodynamics: The Science behind Drug Action Mechanisms

In the complicated world of pharmacology pharmacodynamics is also a place that is a bridge between chemistry and physiology Drugs do something somewhere and this explains how they do it In a simple way pharmacodynamics studies the action of drugs the effects of drugs in terms of their biochemical and physiological effects and how the effects are generated

Fundamentals of Pharmaceutical Formulation Development

The process of changing an active drug substance into a safe and effective drug is much more complicated than it seems at first sight The core of this undertaking is pharmaceutical formulation development a science and strategic field that unites the pursuit of striking a scientific breakthrough and patient care Even the most promising drug molecule would not confer therapeutic benefits without be...

How Mass Spectrometers Are Transforming the Study of Metabolomics

The mechanism of metabolomics can be described as a relatively young science which is rather popular in modern science and investigates metabolites which are the small molecules that take part in the metabolic processes inside the living organism This discipline therefore has great potential as a tool in proactively unraveling a diverse range of biological occurrences disease processes or even tre...

The Future of Pharma Data Management: Creating Unified Platforms for Innovation

Ask a European pharmaceutical executive where the companys data actually lives and the honest answer is usually in about forty places under a dozen owners described in half a dozen vocabularies Research holds assay and translational data Clinical holds trial and subject data

Intelligent Collaborations: Navigating the Current Biopharma M&A Rebound

Biopharma MA didnt collapse in and it recalibrated Deal volumes softened valuations compressed and acquirers grew cautious as macroeconomic headwinds elevated interest rates and regulatory scrutiny made largescale consolidation feel riskier than it once had But the underlying drivers never went away They accumulated

Techno Trends

University of Dundee’s Cabamiquine Shows Promise for Single-Dose Malaria Treatment

Researchers at the University of Dundee have reported encouraging clinical results for cabamiquine a novel antimalarial compound being developed as a potential singledose treatment for malaria

Projects

Genentech to Invest US$750 Million in Oregon Device Fill-Finish Facility

Genentech a member of the Roche Group plans to invest approximately US million in a new device fillfinish manufacturing facility at its acre campus in Hillsboro Oregon The project will add endtoend manufacturing

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys