EDITORIAL SECTION

Articles

Fundamentals of Clinical Pharmacology: Understanding Drug Actions and Ensuring Safety

Clinical pharmacology offers the interface between the philosophies of pharmacology and its application in the actual sense in patient care Fundamentally it is the science which examines the activities of drugs how drugs communicate with biological systems and how such communications result in treatment outcomes or adverse events Clinical pharmacology principles are needed to make sense of how m...

The Unprecedented Surge of Biopharmaceuticals in the European Market

Recent years have seen a significant upheaval in the European pharmaceutical scene marked by an unparalleled surge in biopharmaceutical prominence This shift isnt fleeting but signifies a profound and enduring transformation To fully grasp this paradigm shift its essential to explore the complex interplay of scientific advancements market dynamics regulatory frameworks economic factors and global...

Risk Management in Pharmaceutical Manufacturing

The pharmaceutical industry operates under strict regulatory oversight because medicines directly affect patient health and safety Manufacturers must consistently produce products that meet predefined standards of quality safety efficacy identity strength and purity Achieving these objectives requires a proactive approach to identifying and controlling risks throughout the product lifecycle

Digital Biomarkers and Wearables: Transforming Clinical Trial Data Collection

A participant enrolled in a week pharmaceutical trial may spend fewer than six hours inside a clinical site The remaining odd hours of that year the stairs the fatigue the broken nights the good days and the collapsed ones pass unrecorded Clinical development has quietly accepted this trade for decades building enormous capital decisions on a handful of supervised snapshots taken under artificia...

Chromatography: Principles, Techniques, Applications, and Future Developments

Chromatography is one of the most influential analytical techniques developed in modern science First introduced by Mikhail Tswett in the early twentieth century the technique has evolved into an indispensable tool for separating identifying quantifying and purifying chemical and biological substances

Strategic Partnerships and Collaborations in the European Pharmaceutical Industry

Pharma strategic partnerships are formal agreements in which two or more companies share resources risk and rewards to develop or commercialize medicines In Europe the main models are licensing codevelopment cocommercialization joint ventures and publicprivate consortia Companies choose based on how much risk they want to share how much control they need to keep

Techno Trends

USF Researchers Identify New P. vivax Vaccine Target

Researchers at USF Health have identified a previously unknown vulnerability in Plasmodium vivax a major malaria parasite found across parts of Asia and Central and South America

Projects

Evonik Launches US$94 Million (EUR 80 million) Biotechnology Expansion in Slovakia

Evonik has commenced construction of a new biotechnology expansion at its Fermas facility in Slovensk upa Slovakia The development is part of an approximately US million investment EUR million

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys