EDITORIAL SECTION

Articles

Nanosizing: An Enthralling Strategy to Improve the Systemic Availability of Poorly Soluble Drugs

To enable the effective preclinical testing efficacy and safety evaluation followed by firstinman studies formulation scientists must come up with effective strategies to achieve the desired bioavailability of these poorly soluble compounds

Harnessing the Potential of mRNA Technology for Precision Cancer Treatment

Recent developments in medical research have highlighted the potential of mRNA as a viable approach for addressing challenges in healthcare particularly in combating infectious diseases and cancer

Top 5 Pharma Content Formats That Drive Engagement and Leads

The pharmaceutical business is experiencing a significant change in the way it informs the healthcare professionals decisionmakers and business partners Conventional means of promotion is no longer sufficient in a context whereby buyers do a lot of research before involving themselves with vendors Consequently pharma content marketing has turned out to be a vital instrument of establishing credibi...

Navigating the EU Biosimilars Regulatory Terrain: A Comprehensive Overview

In the everevolving landscape of biological medicines biosimilars have emerged as a costeffective alternative to their reference products For market access in the European Union biosimilars must comply

Manufacturing mRNA, Cell, and Gene Therapies at Commercial Scale

Why Cell and Gene Therapies Fail in Europe After the Science Has Already Worked The uncomfortable statistic for anyone financing advanced therapies in Europe is not the clinical attrition rate It is the withdrawal rate after approval An analysis of advanced therapy medicinal products granted European marketing authorisation found that roughly one in five had subsequently been withdrawn and of th...

Generative AI in Pharma: Scaling Productivity without Compromising

Most enterprise technologies enter a pharmaceutical company through a single door A manufacturing execution system arrives at a site A clinical data platform arrives in development Governance follows the deployment because there is a deployment to govern Generative AI did not behave this way It reached medical writers regulatory managers safety officers market access teams and commercial staff sim...

Techno Trends

University of Dundee’s Cabamiquine Shows Promise for Single-Dose Malaria Treatment

Researchers at the University of Dundee have reported encouraging clinical results for cabamiquine a novel antimalarial compound being developed as a potential singledose treatment for malaria

Projects

Genentech to Invest US$750 Million in Oregon Device Fill-Finish Facility

Genentech a member of the Roche Group plans to invest approximately US million in a new device fillfinish manufacturing facility at its acre campus in Hillsboro Oregon The project will add endtoend manufacturing

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys