EDITORIAL SECTION

Articles

The Role of Technology in Drug Anti-Counterfeiting Efforts

With the rise of drug counterfeiting posing a serious threat to global public health the role of technology in anticounterfeiting efforts has become increasingly vital As counterfeit drugs continue to infiltrate the market

Decision Integrity: The Layer ALCOA+ Was Never Built to Cover

When a model helps make a GxP call the data underneath it can be spotless and the decision still indefensible Here is where the gap opens and the controls that close it For years the discipline that has kept regulated records trustworthy is data integrity We learned ALCOA then ALCOA and built whole quality systems around the idea that a record has to be attributable legible contemporaneous origin...

How AI Could Improve R&D Productivity Across the European Pharma Sector

Few industries invest in the future as heavily as European pharma According to the regions pharmaceutical industry federation the sector invested an estimated billion in research and development in Europe in making it the most researchintensive industry on the continent Yet boards increasingly confront an uncomfortable asymmetry Spending keeps climbing while the outputs that matter most

Enhancing Drug Quality and Efficiency with Smart Manufacturing

Smart manufacturing development leads the pharmaceutical industry toward a substantial industrial shift Current regulatory oversight has created production cost challenges that manufacturers face while managing drug safety requirements for highquality medicine production What are the methods by which technology can change the production methods of drugs What position does automation and artificial...

B2B Lead Generation Pharma: High-ROI Tactics for European Markets

The European pharmaceutical industry can be called one of the most complicated and highly regulated markets in the world In the global market where a centralized approval system under the oversight of the European Medicines Agency EMA is required to the reimbursement systems specific to each country in Germany France Italy Spain and the Nordics market entry and market growth needs the accuracy of...

Digital Health and Wearables: Integration with Pharmaceuticals for Improved Patient Outcomes

Digital health is the application of telecommunication technologies that allow people to control and maintain their health through their smartphone applications sensors and the cloud Mobile devices are while not the only ones an important factor in this digital health environment wearable fitness smart watches and health monitoring devices occupy this niche These wearables can track things as si...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys