EDITORIAL SECTION

Articles

How Mass Spectrometers Are Transforming the Study of Metabolomics

The mechanism of metabolomics can be described as a relatively young science which is rather popular in modern science and investigates metabolites which are the small molecules that take part in the metabolic processes inside the living organism This discipline therefore has great potential as a tool in proactively unraveling a diverse range of biological occurrences disease processes or even tre...

Digital Biomarkers and Wearables: Transforming Clinical Trial Data Collection

A participant enrolled in a week pharmaceutical trial may spend fewer than six hours inside a clinical site The remaining odd hours of that year the stairs the fatigue the broken nights the good days and the collapsed ones pass unrecorded Clinical development has quietly accepted this trade for decades building enormous capital decisions on a handful of supervised snapshots taken under artificia...

The Impact of Digital Health Technologies on Patient Outcomes

It is also noteworthy that the structure of the healthcare system has shifted rather dynamically in the past few years primarily because of the integration of digital health solutions Such developments

The Role of Biopharmaceutics in Early Drug Development

Biopharmaceutics is a major branch in pharmaceutical lores which relates between the physicochemical parcels of a medicine in lozenge form and the pharmacology toxicology or clinical response observed after its administration medicineefficacity and safety are dependent on the dosing authority The optimal lozenge and dosing intervals can be relatively different for different medicines Also for a si...

The Role of Biosimilars in the European Pharma Market: Advancements, Challenges, and Future Perspectives

The European pharmaceutical landscape has undergone remarkable transformations in recent years with the emergence of biosimilars playing a pivotal role in reshaping the industry Before delving into the intricacies of biosimilars

Pharmaceutical Business Strategy: Transformation, Regulation, Outsourcing and Growth

The pharmaceutical industry is standing at an unusual crossroads Patent cliffs are steeper regulators are tougher patients expect more transparency and payers are pushing back harder on price In this environment a strong Pharma Business Strategy is no longer a slide deck exercise for the boardroom its the difference between a company that scales globally and one that quietly fades into irrelevanc...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys