EDITORIAL SECTION

Articles

The Role of Biosimilars in the European Pharma Market: Advancements, Challenges, and Future Perspectives

The European pharmaceutical landscape has undergone remarkable transformations in recent years with the emergence of biosimilars playing a pivotal role in reshaping the industry Before delving into the intricacies of biosimilars

Using Mass Spectrometry as Quality Control in Medicinal Cannabis

Cannabis plants contain a wide variety of complex compounds including phytocannabinoids terpenoids and flavonoids found mainly in the inflorescences Major phytocannabinoids like CBD and THC have beneficial effects on human health

Blockchain in Pharma: Strengthening Drug Traceability, Compliance, and Supply Chain Security

For most of the last decade the European pharmaceutical industry framed supply chain integrity as a packaging problem Put a unique identifier on every pack seal it with an antitampering device check it at the point of dispensing and the falsified medicine threat would be contained Since February that model has been law across the European Union and it has worked better than many sceptics predicte...

Biopharmaceutical Facility Design for Sustainability: A Comprehensive Overview

The design and operation of biopharmaceutical facilities play a pivotal role in shaping the environmental impact of the pharmaceutical industry In recent years there has been a growing emphasis on sustainability within this sector

Why Europe Is Becoming a Strategic Hub for Advanced API Manufacturing

For most of the past three decades API manufacturing was treated as a line item to be minimised Molecules moved east margins improved and European sites were consolidated sold or quietly retired The logic was sound as long as global supply chains behaved predictably They no longer do Pandemicera disruptions recurring shortages of antibiotics and other essential medicines

Artificial Intelligence and Deep/Machine Learning(AI & D/ML) or Artificial Neural Network (ANN): Implications for pharmaceutical product development processes

Producing pharmaceutical products without untoward effects but with desired qualities is not only the very basic requirement set by regulatory authorities but also indirectly decides the success of the pharma industry The pharmaceutical product development process is a combined and coordinated work from numerous divisions of the pharma industry which usually starts

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys