EDITORIAL SECTION

Articles

Robotic Process Automation: The Catalyst for Pharma 4.0 Evolution

The pharmaceutical industry is experiencing a massive shift to new era phase known as Industry or less commonly known as Pharma in this context In the middle of this transformational journey we have Robotic Process Automation RPA as a tool that is disruptive in the way these pharmaceutical organizations are run and managed

Key Stages in Pharmaceutical Formulation Development: A Complete Guide

One of the most significant operations in the field of drug study is pharmaceutical formulation development to ensure that the medications are distributed to the patients without harm and in the most appropriate manner This is a science that involves the transformation of an active pharmaceutical ingredient API into a solid efficient and convenient dosage form To researchers manufacturers and regu...

Advancing Sterile API Manufacturing: Innovations in Next-Generation

For most of the industrys history sterility was a finishedproduct concern Active ingredients were synthesised under conventional good manufacturing practice shipped as bulk powders and rendered sterile only when they reached the fillfinish line usually through filtration or terminal heat That model served simple watersoluble injectables well It serves todays portfolio poorly

Using Mass Spectrometry as Quality Control in Medicinal Cannabis

Cannabis plants contain a wide variety of complex compounds including phytocannabinoids terpenoids and flavonoids found mainly in the inflorescences Major phytocannabinoids like CBD and THC have beneficial effects on human health

European Pharmaceutical Legal Frameworks: Compliance, Legislation and Regulatory Obligations

If youve ever opened the EUs pharmaceutical rulebook and felt your eyes glaze over youre not alone Directives regulations guidelines delegated acts it can feel like reading a legal maze with no exit sign

Business Transformation Strategies for the Pharmaceutical Industry

The pharmaceutical industry is at a crossroads Drug development timelines remain long regulatory scrutiny keeps intensifying and patients now expect the same seamless digital experiences they get from banking apps or online retailers Against this backdrop pharma business transformation has moved from a nicetohave to a survival requirement

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys