EDITORIAL SECTION

Articles

Multi-Omics Integration: Accelerating Precision Drug Development

The economics of pharmaceutical RD are dominated by a single line item that never appears on a balance sheet the programmes that did not work Only about one clinical programme in ten reaches approval and the cost of the nine that do not is carried entirely by the one that does

How Drug Patents Shape the Competitive Landscape in Pharma?

It can rightly be said that the business of pharmaceuticals is very sensitive and crucial since business is all about the manufacturing of change for the purpose of ridding the world of diseases

Sustainable Pharma Manufacturing: Eco-Friendly Practices for the Pharmaceutical Industry

The pharmaceutical business is of significant importance to the healthcare sector all over the world yet it is also among the manufacturing industries that are resourceconsuming Energyintensive production processes complicated chemical synthesis and mass packaging processes have all contributed to pollution and emissions of carbon emissions to the environment as part of the traditional drug manufa...

Fostering Pharma Collaboration: Challenges & Opportunities

In the everevolving world of pharmaceuticals fostering collaboration is essential for driving innovation and meeting the diverse needs of patients However this seemingly simple goal is often hindered by numerous challenges

How Predictive Maintenance Reduces Downtime in Pharma Plants

The pharmaceutical industry is always under stress to enhance the reliability of the production adherence to the regulations and quality of the products without raising the prices and to maintain a continuous supply Machinery malfunctions are not merely a setback in this highstakes game they may compromise batch integrity postpone life and death treatments and put pressure on the market promises

Genomics and Precision Medicine: Exploring the Role of Genomics in Identifying Genetic Markers for Disease Susceptibility and Treatment Response

The advent of genomics has ushered in a new era of healthcare characterized by a paradigm shift from onesizefitsall medicine to precision medicine This transformative approach leverages the power of genetic information to tailor medical interventions to individual patients optimizing treatment efficacy and minimizing adverse effects

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys