EDITORIAL SECTION

Articles

Bispecific Antibodies: Transforming the Future of Oncology

For two decades bispecific antibodies occupied an awkward position in pharmaceutical oncology strategy scientifically compelling commercially unproven and persistently difficult to manufacture That characterisation no longer holds Nineteen bispecific antibodies have been approved globally and combined sales of the class passed twelve billion dollars in with several products now anchoring

Greening the Pill: Pharmaceutical Companies Embrace Environmental Sustainability

In an age where global environmental sustainability is imperative various industries are reassessing their practices to diminish their ecological impact The pharmaceutical sector a crucial component of healthcare is no different This article explores the proactive steps taken by pharmaceutical companies to incorporate sustainability into manufacturing packaging and operations to lessen their envir...

Combination Immunotherapy Trials: Designing the Next Generation of Cancer Drugs

For most of the past ten years the prevailing strategy in immunooncology was addition Checkpoint blockade delivered durable remissions in a minority of patients the intuitive fix was to attach a second agent to a PD or PDL backbone and watch whether response rates moved

B2B Pharma Magazines: Sponsored Thought Leadership Strategies for Brand Authority

The pharmaceutical industry has never been short of innovation Every year brings breakthroughs in biologics advanced therapies AIdriven drug discovery manufacturing automation precision medicine and digital health

COVID-19 Vaccines & SARS-CoV-2 Variants: Who is winning the Race?

It was not uncommon to name the year as annus horribilis as the SARSCoV quickly spread all over the globe causing the first pandemic in years leading to devastating consequences on health economy and the society in general Neither drugs nor vaccines were available for more or less the whole first year of the pandemic causing devastation helplessness and uncertainty Since the beginning of the COV...

Risk Management in Pharmaceutical Manufacturing

The pharmaceutical industry operates under strict regulatory oversight because medicines directly affect patient health and safety Manufacturers must consistently produce products that meet predefined standards of quality safety efficacy identity strength and purity Achieving these objectives requires a proactive approach to identifying and controlling risks throughout the product lifecycle

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys