EDITORIAL SECTION

Articles

Exploring the Versatility of Using 3D Spheroid Models in Research

Cell culture technology forms the foundation of modern biological and pharmaceutical research For many years twodimensional culture systems have served as standard experimental models for studying cellular behavior disease mechanisms and therapeutic responses Although these models contribute significantly to scientific discovery they cannot fully replicate the structural and functional complexity...

10 Essential Factors for Selecting a Pharma Publisher in Europe

European pharmaceutical industry is one of the most progressive professional and productive industries in the world As it is understood researchers aspiring to publish novel papers are interested in credible pharma publishers Selecting appropriate publisher increases the visibility of your work and contributes to societal benefit but choosing wrong publisher decreases the value of your work This g...

Implementing Quality by Design (QbD) in Pharmaceutical Development: Enhancing Product Quality and Regulatory Compliance

Quality by Design QbD stands as a systematic strategy for pharmaceutical development prioritizing predefined product objectives and emphasizing a thorough understanding of both the product and its manufacturing processes This proactive approach integrates quality seamlessly into the development process championing a sciencedriven

From Static PDFs to Usable Digital Forms in Pharmaceutical Operations

Walk through the quality compliance or operations function of almost any pharmaceutical manufacturer and youll find PDF forms everywhere from deviation reports change controls and training records to supplier questionnaires audit checklists and equipment logs Many of these documents exist as PDF files but functionally still behave like paper Someone prints them fills them in by hand

Global CDMO Expansion: Supporting the Growing Advanced Therapy Pipeline

The European advanced therapy sector has spent the better part of two decades proving a scientific point that engineered cells corrected genes and reprogrammed immune systems can deliver durable clinical benefit That argument is now largely settled The question facing pharmaceutical and biotech leadership is industrial rather than scientific whether these therapies can be manufactured consistentl...

Regulatory Challenges in Clinical Testing for New Pharmaceuticals

The clinical testing is a stage where the new pharmaceutical products are a trial on human beings or patients The aims of clinical trials are to assess the effectivenesssafetytolerability or intolerance of new drug in man Generally clinical trials are conducted in phases each phase has different questions regarding the drug

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys