EDITORIAL SECTION

Articles

Ritonavir: How the Discovery of a New Polymorph Changed Drug Development Forever

AIDS is a chronic illness that gained global attention in the s It weakens the immune system of the body making it hard to fight infections When HIV enters the body it targets CD Tcells a type of white blood cell that helps defend against diseases It uses the machinery of Tcells to make new copies of the virus due to which the immune cells are destroyed As the virus spreads and the number of healt...

Key Stages in Pharmaceutical Formulation Development: A Complete Guide

One of the most significant operations in the field of drug study is pharmaceutical formulation development to ensure that the medications are distributed to the patients without harm and in the most appropriate manner This is a science that involves the transformation of an active pharmaceutical ingredient API into a solid efficient and convenient dosage form To researchers manufacturers and regu...

What Are the Benefits of Implementing a Modern MES in Pharma?

The pharmaceutical sector is rapidly changing in a bid to match the increasing pressure of regulation attain perfection in product quality and hasten the timetomarket A Pharma MES or Manufacturing Execution System is one of the most strategic investments that are strategically placed in this environment in terms of operational excellence

AI-Native Pharmaceutical Manufacturing: Transforming the Smart Factory

Most European manufacturing leaders have already paid for a smart factory Sensors were installed historians consolidated execution systems layered over the batch record and dashboards commissioned and mounted on shopfloor screens The plant became visible What it rarely became was decisive Information now moves faster than it did a decade ago yet the decisions that carry real cost and risk

Patient-Centric Clinical Trials: Improving Recruitment, Retention, and Diversity

Patientcentricity has spent a decade as a value statement in pharmaceutical annual reports and comparatively little time as an operating discipline That gap is now closing not because the argument became more persuasive but because the economics and the regulatory environment stopped tolerating the alternative

Exploring the Benefits of Bioassay in Pharmacology

Pharmacology the study of drugs and their effects on living organisms is a multifaceted field crucial to the development and improvement of pharmaceuticals Bioassay a method that assesses the potency of substances

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys