EDITORIAL SECTION

Articles

What Is Clinical Pharmacology and Its Importance for Drug Development and Patient Care

Clinical pharmacology is the critical interface between laboratory science and the education of patients Put simply it is the science that researches the interaction of drugs with the human body and the reaction of the latter to drugs People pose the question what is clinical pharmacology The solution can be found in its multidisciplinary character of the matter combining pharmacology medicine ge...

European Pharmaceutical Commercial Strategy: Pricing, Market Access and Investment Decisions

Picture a midsized biotech with a strong new therapy The EMA approval arrives on schedule the team celebrates and the forecast shows a smooth European rollout Then reality sets in One country asks for a different comparator Another wants realworld data you havent

How Pharmacoepidemiology Drives Clinical Research: Exploring Trends and Insights

The pharmaceutical industry operates within a complex regulatory framework aimed at ensuring the safety efficacy and quality of medicinal products

mRNA Therapeutic Modalities Design, Formulation and Manufacturing under Pharma 4.0 Principles

During recent decades biopharmaceuticals such as monoclonal antibodies peptides or nucleic acids have gained impressive attention as revolutionary therapeutics and vaccine strategies attempting to fulfil the high expectations of resolving serious health conditions Regarding nucleic acids DNA and mRNAbased technologies have been established as extremely promising approaches in therapy and preventio...

The Future of Pharma and CRO Operations: A Practical Guide to Automation

Many pharmaceutical leaders assume productivity gains will come from copilots conversational tools that help staff draft text or find information faster Yet copilots remain confined to the surface of work They assist with isolated tasks but cannot follow a process through to completion They do not manage clinical operations budgets or respond to RFPs for instance

How Pharma 4.0 Is Revolutionizing Drug Manufacturing

The pharmaceutical industry in the world is experiencing a digital transformation rejuvenated by the advent of Pharma an industry phenomenon that is based on Industry Due to the readjustment of the manufacturing industry to Industry the automation data interchange and intelligent ecosystem the pharmaceutical ecosystem is similarly being reorganized with Pharma technologies Research and develo...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys