EDITORIAL SECTION

Articles

The Future of Pharma and CRO Operations: A Practical Guide to Automation

Many pharmaceutical leaders assume productivity gains will come from copilots conversational tools that help staff draft text or find information faster Yet copilots remain confined to the surface of work They assist with isolated tasks but cannot follow a process through to completion They do not manage clinical operations budgets or respond to RFPs for instance

Pharma Email Marketing Europe: Personalized Campaigns for C-Suite Leads

The pharmaceutical industry is a very competitive industry and to reach the decisionmakers a focused and strategic marketing strategy is necessary Conventional marketing is not often precise enough to reach executives that drive buying alliances and strategic relationships Here the pharma email marketing has come to play as a potent instrument of relationship establishment with the key stakeholder...

Strengthening Clinical Trials Through Digital and Decentralized Technologies

For most of the past halfcentury the clinical trial has been organised around the investigator site Participants travelled to hospitals data were recorded at the clinic and monitors travelled again to verify them That model produced the evidence behind modern medicine but it asks a great deal of the people it depends on patients who must take time off work arrange care for dependants and cross reg...

The Evolving Role of AI in Pharmaceutical Commercial Strategy

For most of the past decade the pharmaceutical industry told its artificial intelligence story from the laboratory bench Molecule generation protein structure prediction and trial simulation captured the headlines and the capital Yet the economics of this industry have never been settled in discovery alone

Digital Twins in Pharma: What They Are and Why They Matter

In the current fastpaced life sciences industry Digital Twins Pharma innovations are transforming the industrys conceptualization design testing and delivery of therapeutic products Since intelligent connected and datadriven operations have taken the center stage in pharma companies moving towards the digital age the emergence of Digital Twin Technology in Pharmaceutical structures has been a focu...

Bispecific Antibodies: Transforming the Future of Oncology

For two decades bispecific antibodies occupied an awkward position in pharmaceutical oncology strategy scientifically compelling commercially unproven and persistently difficult to manufacture That characterisation no longer holds Nineteen bispecific antibodies have been approved globally and combined sales of the class passed twelve billion dollars in with several products now anchoring

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys