EDITORIAL SECTION

Articles

Oral Obesity Medicines: How Pills Could Change the European GLP-1 Market

For a decade the European obesity market has been defined by a needle a fridge and a specialist clinic In July that definition broke The European Commission granted marketing authorisation for a oncedaily mg oral semaglutide tablet making it the first GLP receptor agonist

The Rise of Personalized Medicine in Europe: Opportunities and Challenges for Pharma Companies

In Europe there is a growing momentum around personalized medicine an inventive method that customizes medical treatments based on individual characteristics As progress in genomics and molecular diagnostics advances

Drug Safety in Focus: Challenges and Solutions for Pharma Companies

Drug safety is a paramount concern for pharmaceutical companies worldwide Ensuring the safety and efficacy of medications is not only a legal requirement but also a moral obligation towards patient welfare

Designing Early-stage Formulation Strategies for Anti-microbial Peptides (Amps): A Major Prerequisite for Combating Anti-microbial Resistance

At present the world is witnessing an exponential increase in antimicrobial resistance AMR making it important for us to search alternatives to antibiotics in order to combat multidrug resistant MDR bacterial infections According to a study drugresistant infections were responsible for million deaths in globally The number of predicted deaths

Personalized Medicine and Longevity: Advancing the Frontier

The world is experiencing a profound demographic shift with population aging impacting healthcare economies and human rights The United Nations projects that by the number of people aged and over will double to billion comprising one in six people worldwide United Nations OHCHR By older adults will likely outnumber children necessitating a rethink of health aging and longevity Hartmann Young

The Unprecedented Surge of Biopharmaceuticals in the European Market

Recent years have seen a significant upheaval in the European pharmaceutical scene marked by an unparalleled surge in biopharmaceutical prominence This shift isnt fleeting but signifies a profound and enduring transformation To fully grasp this paradigm shift its essential to explore the complex interplay of scientific advancements market dynamics regulatory frameworks economic factors and global...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys