EDITORIAL SECTION

Articles

Breaking Down Barriers: Advancements in Biodegradable Drug Delivery

In todays world where sustainability is a top priority breaking down barriers to a greener future is crucial One area where advancements are being made is in the field of biodegradable drug delivery

Plant-derived Edible Nanoparticles in Delivering Cancer Drugs: Fact or Fad?

Plantderived edible nanoparticles PDENPs are nanosizedvesicles obtained from edible plants such as grapefruit curcumin ginger broccoli and lemon They contain miRNAs bioactive lipids and proteins which play an important role in cell signaling regulation of plant immunity and transport of bioactive molecules into mammalian cells As the world attempts to overcome

Bispecific Antibodies: Transforming the Future of Oncology

For two decades bispecific antibodies occupied an awkward position in pharmaceutical oncology strategy scientifically compelling commercially unproven and persistently difficult to manufacture That characterisation no longer holds Nineteen bispecific antibodies have been approved globally and combined sales of the class passed twelve billion dollars in with several products now anchoring

Quality by Design Is a Mindset, Not a Milestone

Every medicine is a promise about consistency The tablet dispensed in Milan next spring must behave exactly like the one tested in a trial four years earlier and like the ten million made between them

Building Patient-Centric Clinical Trials: Technologies, Strategies, and Regulatory Considerations

Patientcentricity in clinical trials represents a crucial cultural and operational transformation in the development and evaluation of new treatments The patient experience has evolved from a secondary consideration to a central priority in trial design driven by

Implementing Quality by Design (QbD) in Pharmaceutical Development: Enhancing Product Quality and Regulatory Compliance

Quality by Design QbD stands as a systematic strategy for pharmaceutical development prioritizing predefined product objectives and emphasizing a thorough understanding of both the product and its manufacturing processes This proactive approach integrates quality seamlessly into the development process championing a sciencedriven

Techno Trends

University of Dundee’s Cabamiquine Shows Promise for Single-Dose Malaria Treatment

Researchers at the University of Dundee have reported encouraging clinical results for cabamiquine a novel antimalarial compound being developed as a potential singledose treatment for malaria

Projects

Genentech to Invest US$750 Million in Oregon Device Fill-Finish Facility

Genentech a member of the Roche Group plans to invest approximately US million in a new device fillfinish manufacturing facility at its acre campus in Hillsboro Oregon The project will add endtoend manufacturing

Research Insights

Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

The development of effective strategies for treating bone defects can be based on gene therapy methods aimed at regulating the differentiation of osteoprogenitor cells One of the approaches is to use siRNA mo

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys