EDITORIAL SECTION

Articles

Access to Affordable Medicines: A Persistent Challenge for Europe

The problem of affordable medicines has been topical in Europe for many years Despite the fact that there are well developed health units in many regions of the world and particularly in this continent the health challenges of the population have not been fully met especially in access to affordable basic medicines This problem is relevant not only to the patients but also to the stability of heal...

Beyond Trial Completion: Post-Trial Responsibilities and Effective Dissemination of Clinical Research

Clinical trials are the cornerstone of evidencebased medicine and pharmaceutical innovation Through the systematic evaluation of interventions they provide the evidence required to assess efficacy safety and value for patients and healthcare systems However the completion of participant followup does not signify the completion of a trials ethical and scientific obligations

How Drug Patents Shape the Competitive Landscape in Pharma?

It can rightly be said that the business of pharmaceuticals is very sensitive and crucial since business is all about the manufacturing of change for the purpose of ridding the world of diseases

Quantum Dot: The Future of Personalized Medicine

Cancer is amongst the most significant health hazards around the globe Individualized chemotherapy offers promise for the forthcoming cancer therapy in clinical practice with each patient receiving tailored medication based on essential biological aspects of a specific tumor One of the most pressing issues is the development of innovative ways for personalized

The Role of European Pharma in Global Healthcare Advancements

Europe is one of the largest players in the international market for health care due to research development and innovation and competitive pharmaceutical industries Some of these European pharma medical research organizations and health care systems have continually provided valuable solutions to the welfare of people globally It is an increasingly important role for them to play given that they...

Antibody-Drug Conjugates (ADCs): Driving the Next Generation of Precision Oncology

An antibodydrug conjugate is a targeted cancer therapy that links a potent cytotoxic drug to a monoclonal antibody through a chemical linker so the antibody delivers the payload directly to tumour cells expressing a chosen antigen The design widens the therapeutic window it concentrates cytotoxic activity where the target is expressed and limits the systemic exposure that constrains conventional c...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys