EDITORIAL SECTION

Articles

From Digital Transformation to Intelligent Pharma: How AI Is Reshaping Pharmaceutical Strategy

Pharmas digital transformation has solved one problem well access to information Market signals arrive continuously Commercial teams generate customer and channel data medical and scientific functions accumulate new evidence and supply and finance teams produce operational signals that enterprise platforms can now connect across what were once separate systems

Role of QSAR in filling in the gaps of CoVID-19 Therapeutics

Since initial reports from Wuhan China in December and the subsequent declaration of a global pandemic by the WHO in March CoVID has precipitated the greatest health crisis in modern history While exposing fundamental weaknesses in healthcare systems across the globe this tragedy has also been an opportunity for scientists and researchers in different fields to collaborate and produce solutions...

The Future of Pharma Data Management: Creating Unified Platforms for Innovation

Ask a European pharmaceutical executive where the companys data actually lives and the honest answer is usually in about forty places under a dozen owners described in half a dozen vocabularies Research holds assay and translational data Clinical holds trial and subject data

Precision Oncology Trials: Navigating the Future of Cancer Care

Precision oncology is revolutionizing cancer care offering targeted treatments tailored to each patients unique genetic makeup As we navigate the future of cancer care precision oncology trials are paving the way for more effective and personalized treatment options

10 Effective Strategies to Reduce Water Waste in Pharmaceutical Manufacturing

Water is a resource of great concern to pharmaceutical manufacturing since it is essential in the cleaning of equipment used in manufacturing operations as well as in drug formulations Nevertheless the pharmaceutical industry presents another leading water consumer and therefore reduction of water wastes should be at the top of the agenda regarding sustainability

Why Europe Is Becoming a Strategic Hub for Advanced API Manufacturing

For most of the past three decades API manufacturing was treated as a line item to be minimised Molecules moved east margins improved and European sites were consolidated sold or quietly retired The logic was sound as long as global supply chains behaved predictably They no longer do Pandemicera disruptions recurring shortages of antibiotics and other essential medicines

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys