EDITORIAL SECTION

Articles

Chromatography: Principles, Techniques, Applications, and Future Developments

Chromatography is one of the most influential analytical techniques developed in modern science First introduced by Mikhail Tswett in the early twentieth century the technique has evolved into an indispensable tool for separating identifying quantifying and purifying chemical and biological substances

Artificial Intelligence in Pharmacy: A New Era of Drug Development and Personalized Care

Traditional pharmaceutical systems depend significantly on manual processes making drug development slow errorprone and inefficient New drug synthesis is a process that requires a lot of effort and time including stages such as lead compound identification and optimization and these are mostly done by trial and error The revolutionary development of artificial intelligence AI is that it can automa...

Prescription Drugs and Personalized Medicine: A New Era in Pharma

The field of medicine is rapidly evolving and one of the most exciting advancements is personalized medicine This approach tailors medical treatment to the individual characteristics of each patient

Genetic Testing in Mainstream Medicine: Driving Precision, Prevention, and Population Health

Healthcare systems globally are shifting toward valuebased care where reimbursement is tied to outcomes not procedures Genetic testingparticularly multigene panels and polygenic risk scores is emerging as a highimpact enabler of early intervention and targeted prevention reducing longterm costs and improving clinical outcomes

What Is Clinical Pharmacology and Its Importance for Drug Development and Patient Care

Clinical pharmacology is the critical interface between laboratory science and the education of patients Put simply it is the science that researches the interaction of drugs with the human body and the reaction of the latter to drugs People pose the question what is clinical pharmacology The solution can be found in its multidisciplinary character of the matter combining pharmacology medicine ge...

Decision Integrity: The Layer ALCOA+ Was Never Built to Cover

When a model helps make a GxP call the data underneath it can be spotless and the decision still indefensible Here is where the gap opens and the controls that close it For years the discipline that has kept regulated records trustworthy is data integrity We learned ALCOA then ALCOA and built whole quality systems around the idea that a record has to be attributable legible contemporaneous origin...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys