EDITORIAL SECTION

Articles

Gene Therapy: Breakthrough Treatments for Rare Diseases

The idea of gene therapy is radically changing the sphere of medicine with the possibilities to cure the patients with the rare hereditary diseases These diseases which are usually brought about by the alteration of the sequence

The Future of Pharma Data Management: Creating Unified Platforms for Innovation

Ask a European pharmaceutical executive where the companys data actually lives and the honest answer is usually in about forty places under a dozen owners described in half a dozen vocabularies Research holds assay and translational data Clinical holds trial and subject data

The Architect of the Void: When 3D Printing Becomes the Body’s New Bone

In the quiet pressurised hum of a modern surgical suite a surgeon holds a highdefinition scan of a young patients femur On the screen a jagged dark shadow marks where an osteosarcoma has claimed its territory For decades the script for this moment has been written in cold hard steel

The Future of Pharma and CRO Operations: A Practical Guide to Automation

Many pharmaceutical leaders assume productivity gains will come from copilots conversational tools that help staff draft text or find information faster Yet copilots remain confined to the surface of work They assist with isolated tasks but cannot follow a process through to completion They do not manage clinical operations budgets or respond to RFPs for instance

B2B Lead Generation Pharma: High-ROI Tactics for European Markets

The European pharmaceutical industry can be called one of the most complicated and highly regulated markets in the world In the global market where a centralized approval system under the oversight of the European Medicines Agency EMA is required to the reimbursement systems specific to each country in Germany France Italy Spain and the Nordics market entry and market growth needs the accuracy of...

Understanding Pharmacodynamics: The Science behind Drug Action Mechanisms

In the complicated world of pharmacology pharmacodynamics is also a place that is a bridge between chemistry and physiology Drugs do something somewhere and this explains how they do it In a simple way pharmacodynamics studies the action of drugs the effects of drugs in terms of their biochemical and physiological effects and how the effects are generated

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys