EDITORIAL SECTION

Articles

Digital Biomarkers and Wearables: Transforming Clinical Trial Data Collection

A participant enrolled in a week pharmaceutical trial may spend fewer than six hours inside a clinical site The remaining odd hours of that year the stairs the fatigue the broken nights the good days and the collapsed ones pass unrecorded Clinical development has quietly accepted this trade for decades building enormous capital decisions on a handful of supervised snapshots taken under artificia...

Assessing the Impact of Tariffs on the Pharmaceutical Industry

The pharmaceutical industry function as a vital foundation for worldwide healthcare infrastructure because they push medical advancement while supporting medication availability to patients The pharmaceutical industry deals with major operational obstacles when public authorities establish tariffs for both pharmaceutical imports and exports The implementation of tariffs affects how prices shift wh...

AI-Native Pharmaceutical Manufacturing: Transforming the Smart Factory

Most European manufacturing leaders have already paid for a smart factory Sensors were installed historians consolidated execution systems layered over the batch record and dashboards commissioned and mounted on shopfloor screens The plant became visible What it rarely became was decisive Information now moves faster than it did a decade ago yet the decisions that carry real cost and risk

The 2025 Agenda: Navigating New European Compliance Challenges in Pharma

EU pharma industry expectate new regulations changes in the year European Medicines Agency EMA and other regulatory authorities in the continent gradually increase regulatory requirements that exercise greater pressure on business entities to implement patientoriented sustainable and innovative production standards

The Competitive Generic Therapy (CGT)

Generic medications are critical in the healthcare sector due to their affordability and accessibility to the public while maintaining comparable quality efficacy and safety to that of branded products Generic medications research and development followed by commercialisation also fosters competition and innovation within the pharmaceutical

AI-Native R&D: Transforming Drug Discovery Through Intelligent Automation

For four decades pharmaceutical research productivity has moved stubbornly in the wrong direction A new medicine still takes ten to fifteen years to reach patients at a capitalised cost approaching US billion

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys