EDITORIAL SECTION

Articles

Bispecific Antibodies: Transforming the Future of Oncology

For two decades bispecific antibodies occupied an awkward position in pharmaceutical oncology strategy scientifically compelling commercially unproven and persistently difficult to manufacture That characterisation no longer holds Nineteen bispecific antibodies have been approved globally and combined sales of the class passed twelve billion dollars in with several products now anchoring

Medical Devices and Pharma: A Symbiotic Relationship for Improved Healthcare

The healthcare industry is continually evolving driven by technological advancements and innovative approaches to patient care Among the most significant developments is the symbiotic relationship between medical devices

EU Pharma Reform 2025 Explained: What Market Access Leaders Must Know for 2026-2029

What if your EU market exclusivity depends on launching your medicine in every member state and proving its realworld value This is no longer hypothetical The historic Pharma Reform agreement of the Council of the EU of March is the first major revision of pharmaceutical legislation in more than years It will have a significant impact on the way businesses will enter the market set their prices...

The Future of Tissue-Targeted Lipid Nanoparticle-Mediated Nucleic Acid Delivery

The earliest example of in vivo expression of exogenous mRNA was by direct intramuscular injection in mice without the aid of a delivery vehicle This appears to defy what is known about nucleic acids being that they are large polar and metabolically unstable drugs that do not cross cell membranes However since cytoplasmic delivery is essential for mRNA transcription

The Impact of Inflation and New Policies on Drug Pricing

Drug pricing has long been a contentious issue balancing the cost of innovation and the need for accessible healthcare In recent years the landscape has grown more complex due to rising inflation

Digital Twins in Pharma: What They Are and Why They Matter

In the current fastpaced life sciences industry Digital Twins Pharma innovations are transforming the industrys conceptualization design testing and delivery of therapeutic products Since intelligent connected and datadriven operations have taken the center stage in pharma companies moving towards the digital age the emergence of Digital Twin Technology in Pharmaceutical structures has been a focu...

Techno Trends

Lilly’s Olomorasib Gains FDA Breakthrough Therapy Status

Eli Lilly and Company has secured Breakthrough Therapy designation from the US Food and Drug Administration FDA for olomorasib an investigational medicine being developed for adults with advanced pancreatic cancer carrying a KRAS GC mutation

Projects

Resilience and Lilly Expand Ohio Manufacturing Facility with US$750 Million Investment

Resilience a technologydriven contract development and manufacturing organisation CDMO has expanded its strategic partnership with Eli Lilly and Company to increase domestic production

Research Insights

Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

The development of effective strategies for treating bone defects can be based on gene therapy methods aimed at regulating the differentiation of osteoprogenitor cells One of the approaches is to use siRNA mo

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys