EDITORIAL SECTION

Articles

Artificial Intelligence and Deep/Machine Learning(AI & D/ML) or Artificial Neural Network (ANN): Implications for pharmaceutical product development processes

Producing pharmaceutical products without untoward effects but with desired qualities is not only the very basic requirement set by regulatory authorities but also indirectly decides the success of the pharma industry The pharmaceutical product development process is a combined and coordinated work from numerous divisions of the pharma industry which usually starts

The Future of Tissue-Targeted Lipid Nanoparticle-Mediated Nucleic Acid Delivery

The earliest example of in vivo expression of exogenous mRNA was by direct intramuscular injection in mice without the aid of a delivery vehicle This appears to defy what is known about nucleic acids being that they are large polar and metabolically unstable drugs that do not cross cell membranes However since cytoplasmic delivery is essential for mRNA transcription

Efficiency in Bioprocessing: Unveiling Upstream and Downstream Operations

Bioprocessing plays a crucial role in the pharmaceutical biotechnology and healthcare industries ensuring the efficient production of biologics vaccines and other biobased products

Unveiling Opportunities: Trends and Analysis in the European Pharmaceutical Market

The European pharmaceutical market stands at the forefront of global healthcare playing a pivotal role in the development and distribution of lifesaving medications Renowned for its innovative research and commitment to healthcare excellence the industry is experiencing dynamic shifts that demand the unwavering attention of BB stakeholders With a profound emphasis on precision medicine digital hea...

Fundamentals of Clinical Pharmacology: Understanding Drug Actions and Ensuring Safety

Clinical pharmacology offers the interface between the philosophies of pharmacology and its application in the actual sense in patient care Fundamentally it is the science which examines the activities of drugs how drugs communicate with biological systems and how such communications result in treatment outcomes or adverse events Clinical pharmacology principles are needed to make sense of how m...

How Mass Spectrometers Are Transforming the Study of Metabolomics

The mechanism of metabolomics can be described as a relatively young science which is rather popular in modern science and investigates metabolites which are the small molecules that take part in the metabolic processes inside the living organism This discipline therefore has great potential as a tool in proactively unraveling a diverse range of biological occurrences disease processes or even tre...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

One-month physicochemical stability study of idarubicin prepared in polyolefin-type bags for the treatment of hematological diseases

Idarubicine is a mainstay of the treatment strategy for hematological cancer The literature lacks stability data that comply with current preparation practices and recommendations for conducting stability studies

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys