EDITORIAL SECTION

Articles

Cybersecurity in Pharma: The Threat No One Budgeted For

There is a particular kind of risk that organisations are bad at pricing the one that has never happened to them Pharmaceutical companies have spent a generation building sophisticated defences against the risks they know intimatelycontamination adulteration deviation recall Quality systems are mature inspectionready and deeply funded Cyber risk has never enjoyed that status It sat in the IT budge...

Revolutionizing Healthcare with Innovative Therapeutics

Revolutionizing healthcare with innovative therapeutics involves the development and application of groundbreaking treatments and approaches that significantly improve patient outcomes reduce costs and enhance overall healthcare effectiveness

mRNA Technology: Unlocking New Possibilities In Therapeutics Beyond Vaccines

In the last few years the mRNA has emerged as a discovery of the century in what concerns biotechnology and medicine Although it has emerged on the global level during the search for COVID vaccines it is used in many other ways Scientists and big pharmacy companies are now investigating virtually all possible uses of mRNA from highly targeted treatments to diseases that had no cure before

Spleen Cytokines Against Inflammatory Bowel Disease

Over one hundred years ago at the University of Toronto Frederick Banting Charles Best and James Collip extracted protein insulin from the pancreas that saved the lives of millions of diabetics since then It is possible that the proteins extracted from the spleen can also help people with inflammatory bowel disease IBD

Digital Twins in Pharmaceutical R&D: Simulating Biology for Faster Innovation

For most of its modern history pharmaceutical research has been an experimental science with a statistical conscience Build the molecule dose the animal run the trial count the failures and let the survivors pay for everything that did not make it That arrangement has become progressively harder to defend Attrition remains concentrated in the phases where money has already

Pharma Patent Expirations: How European Generics are changing the Market

The industry whereby most products are pharmaceuticals is usually fueled by innovation research and last but not the least patents Patents enable drug manufacturers to sell a new drug for a certain amount of time so they can indeed recover their research and development costs However once the patents for the medicine expire any different company can legally manufacture the copy of the same drug a...

Techno Trends

Alume Biosciences Secures FDA Breakthrough Therapy Designation for Bevonescein

Alume Biosciences has received Breakthrough Therapy Designation BTD from the US Food and Drug Administration FDA for bevonescein an investigational fluorescent drug being developed to support realtime nerve visualisation during head and neck surgery in adults Bevonescein is an intravenous fluorescent peptidedye conjugate that binds to nerve tissue

Projects

SK pharmteco Plans More Than US$200 Million Investment in Small Molecule and Peptide Manufacturing

SK pharmteco is planning a fiveyear investment of more than US million to expand and modernise its pharmaceutical development and manufacturing operations in the United States The programme will strengthen capabilities for small molecules and peptides while supporting a more

Research Insights

A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG

PIGACDG is a congenital disorder of glycosylation caused by pathogenic partial lossoffunction variants in the PIGA gene PIGA encodes an enzyme responsible for the catalytic transfer of Nacetylglucosamine

whitepaper

Post-Translational Modifications in Drug Discovery: From Molecular Regulation to Clinical Impact

For decades the central dogma of molecular biology has anchored our understanding of cellular function DNA to RNA to protein But this linear view is incomplete A growing body of evidence shows that much of biologys