App Notes
High-Throughput Cytometry for MSC Identity & Differentiation
Accurate assessment of mesenchymal stem cell (MSC) identity and differentiation is essential in both research and clinical applications—especially in the fast-moving field of regenerative medicine.
Achieve Compliance in Ligand Binding Assays with Octet® BLI Systems
Octet® systems enable analytical assessment of biologics in various stages of the development workflow beginning with discovery and early selection to validation, manufacturing and quality control.
High-Throughput Biosimilarity Assessment with Octet® BLI Systems
Demonstrating biosimilarity throughout upstream and downstream production processes is crucial. However, screening all potential candidates using standard analytical methods can be challenging. To overcome this, an alternative high-throughput analytical approach is needed. In this application note, we showcase the ability to rapidly test a Humira® biosimilar (adalimumab) development sample against three key ligands, meeting regulatory requirements.
Optimizing Fc Gamma Receptor-IgG Interaction Analysis with the Octet® BLI Platform
A major mechanism of action for therapeutic monoclonal antibodies is the initiation of effector function via binding to Fc gamma receptors (FcγRs) expressed on the surface of immune effector cells. The ability of therapeutic monoclonal antibodies to bind FcγRs can greatly impact their safety and efficacy, and as such, efforts to analyze and enhance Fc interactions with FcγRs are an integral part of biotherapeutic development processes.
Accelerate Biosimilar Development with High-Throughput Kinetic Screening
As the biosimilar market continues to expand, the need for efficient, cost-effective, and reliable development processes becomes paramount.
Unlock the Future of Neuroscience Research with iPSC-Derived Models
Advance Your In Vitro Studies with Growth Factors and Live-Cell Analysis
Streamline Bioprocess Monitoring with Automated LC-MS Analytics
Accelerate your bioprocess with Waters Bioprocess Walk-Up Solutions. Automate critical process parameters (CPPs) and product quality attributes (PQAs) analysis, from nutrient monitoring to protein titer evaluation.
