Boosting biomanufacturing with optimized cell culture media: Comparing animal-derived cholesterol with synthetic PhytoChol® BioPharma

In modern biomanufacturing, consistency, purity, and safety are critical—especially when producing therapeutic proteins, vaccines, and viral vectors. Cholesterol, a key ingredient in cell culture media, plays a vital role in improving cell growth and enhancing production outcomes of bioprocesses which use partially or fully cholesterol-auxotroph cell lines, including insect cells, NS0 cells, Vero cells and MSCs. Traditional sources from animal products bring variability, contamination risks, and ethical concerns.

Evonik introduces PhytoChol® BioPharma – a high-purity, synthetic cholesterol that delivers consistent performance and increases the sustainability of your processes.

What You Will Learn:

• Why cholesterol is crucial for cell culture success.
• Side-by-side study results comparing PhytoChol® BioPharma vs. animal-derived cholesterol.
• How PhytoChol® BioPharma supports robust cell proliferation and stemness.
• Strategies to reduce risk and variability in bioproduction.