Pharma Articles
Articles are written by renowned pharmaceutical company executives and other professionals from across the world on important topics relating to the business. The part of articles on the pharmaceutical industry focuses on current and developing concerns in fields such as pharmaceutical R&D, drug discovery, clinical trials, pharmaceutical production, biopharmaceuticals, and information technology.
From Molecule to Market: Building a Regulatory-Ready Manufacturing Strategy
Every pharmaceutical executive can recite the journey from molecule to market Far fewer can say with confidence at which point in that journey their manufacturing strategy became capable of withstanding a regulatory inspection The distinction matters more than it once did Approval timelines are comp...
Combination Immunotherapy Trials: Designing the Next Generation of Cancer Drugs
For most of the past ten years the prevailing strategy in immunooncology was addition Checkpoint blockade delivered durable remissions in a minority of patients the intuitive fix was to attach a second agent to a PD or PDL backbone and watch whether response rates moved
From Digital Transformation to Intelligent Pharma: How AI Is Reshaping Pharmaceutical Strategy
Pharmas digital transformation has solved one problem well access to information Market signals arrive continuously Commercial teams generate customer and channel data medical and scientific functions accumulate new evidence and supply and finance teams produce operational signals that enterprise pl...
The Evolving Role of AI in Pharmaceutical Commercial Strategy
For most of the past decade the pharmaceutical industry told its artificial intelligence story from the laboratory bench Molecule generation protein structure prediction and trial simulation captured the headlines and the capital Yet the economics of this industry have never been settled in discover...
Exploring the Versatility of Using 3D Spheroid Models in Research
Cell culture technology forms the foundation of modern biological and pharmaceutical research For many years twodimensional culture systems have served as standard experimental models for studying cellular behavior disease mechanisms and therapeutic responses Although these models contribute signifi...
The Future of Pharma Data Management: Creating Unified Platforms for Innovation
Ask a European pharmaceutical executive where the companys data actually lives and the honest answer is usually in about forty places under a dozen owners described in half a dozen vocabularies Research holds assay and translational data Clinical holds trial and subject data
Chromatography: Principles, Techniques, Applications, and Future Developments
Chromatography is one of the most influential analytical techniques developed in modern science First introduced by Mikhail Tswett in the early twentieth century the technique has evolved into an indispensable tool for separating identifying quantifying and purifying chemical and biological substanc...
Manufacturing mRNA, Cell, and Gene Therapies at Commercial Scale
Why Cell and Gene Therapies Fail in Europe After the Science Has Already Worked The uncomfortable statistic for anyone financing advanced therapies in Europe is not the clinical attrition rate It is the withdrawal rate after approval An analysis of advanced therapy medicinal products granted Europe...
Patient-Centric Clinical Trials: Improving Recruitment, Retention, and Diversity
Patientcentricity has spent a decade as a value statement in pharmaceutical annual reports and comparatively little time as an operating discipline That gap is now closing not because the argument became more persuasive but because the economics and the regulatory environment stopped tolerating the...
Multi-Omics Integration: Accelerating Precision Drug Development
The economics of pharmaceutical RD are dominated by a single line item that never appears on a balance sheet the programmes that did not work Only about one clinical programme in ten reaches approval and the cost of the nine that do not is carried entirely by the one that does
