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Converging Innovations to Break Barriers in Neural Drug Discovery

RealBrain® microtissues, a family of class-leading 3D organotypic neural models, offer human-relevant alternatives to traditional animal models for high-throughput screening of potential drug candidates. These models mature quickly, are highly scalable, and provide optical clarity to visualize neural networks. Tessara's unique biomaterials, combined with the speed and precision of the Formulatrix F.A.S.T.TM liquid handler, enable the encapsulation of neural stem cells into 3D microtissues, ready for assays within just three weeks.

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You will learn from this webinar:

  • RealBrain® microtissues as human-relevant alternatives to traditional animal models for drug screening.
  • Rapid maturation and scalability of RealBrain® 3D organotypic neural models.
  • Optical clarity of RealBrain® models for visualizing neural networks.
  • Tessara's unique biomaterials for encapsulating neural stem cells into 3D microtissues.
  • Quick preparation of 3D microtissues for assays within 3 weeks.
  • Features and benefits of the Formulatrix F.A.S.T. Liquid Handler.
  • High precision of the F.A.S.T. at sub-microliter volumes without liquid class optimization.
  • Rapid liquid transfers using F.A.S.T.'s 96-channel head in 96- and 384-well plates.
  • Application of the F.A.S.T. in high-throughput assays.
  • Integration of RealBrain® technology with the F.A.S.T. liquid handler for producing 3D neural models in a 96-well format.
  • Enhanced reproducibility and scalability in drug development using these technologies.

Who should attend:

  • Pharmaceutical and biotechnology researchers
  • Neuroscientists and biomedical engineers
  • High-throughput screening and drug development professionals
  • Academic and clinical researchers in neural studies
  • Laboratory managers and technicians
  • Professionals involved in alternative methods to animal testing
  • Students and educators in biomedical and pharmaceutical sciences

Speakers:

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Dr. Usman Ashraf

Dr. Usman Ashraf is an Application Scientist at Formulatrix, responsible for liquid handling systems and their applications in life science areas. He received his Ph.D. in Molecular Biology, where his research focused on targeting viral genomes using CRISPR/Cas technology. Before joining Formulatrix, he worked as an associate researcher and instructor at Lahore University of Management Sciences (LUMS), Pakistan.

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Dr. Mark Greenough

Dr. Mark Greenough is the Principal Scientist for Tessara Therapeutics. Leveraging over a decade of experience in neuroscience research, he is engineering a pipeline of disease-relevant RealBrain® microtissues such as ADBrain™, a ‘first of its kind’ 3D cell model that displays pathological hallmarks of Alzheimer’s disease.